Recombinant CD31 antibody (Extracellular Domain)
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- Target See all CD31 (PECAM1) Antibodies
- CD31 (PECAM1) (Platelet/endothelial Cell Adhesion Molecule (PECAM1))
- Antibody Type
- Recombinant Antibody
- Fragment
- single-domain Antibody (sdAb)
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Binding Specificity
- Extracellular Domain
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Reactivity
- Human
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Host
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Alpaca
- Expression System
- E.coli
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Clonality
- Multiclonal
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Conjugate
- This CD31 antibody is un-conjugated
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Application
- Immunofluorescence (IF), Immunofluorescence (fixed cells) (IF/ICC), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Purpose
- Alpaca anti-human CD31 VHH is a carefully developed and validated nanobody (single-domain antibody) binding to human CD31 (PECAM-1) highly suitabe for tissue staining.
- Brand
- LIMAAbody®
- Specificity
- Detects endogenous levels of total human CD31 protein.
- Cross-Reactivity (Details)
- does not cross-react with mouse CD31 based on qualitative analysis
- Characteristics
- VHH protein tag: C-terminal (6x) His-Tag
- Purification
- Affinity-purified antibody fragment.
- Immunogen
- Recombinant protein containing the extracellular domain of murine CD31 protein.
- Clone
- 2MAC4-2PEC47-3MAC24-3MAC69-3MAC82-3PEC92
- Top Product
- Discover our top product PECAM1 Primary Antibody
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- Application Notes
- Immunofluorescence: 10 μg/mL (frozen sections), 5 μg/mL (cell culture), 20 μg/mL (wholemount)
- Comment
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VHH protein tag: C-terminal (6x) His-Tag
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS, pH 7.4, 0.02% sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Do not freeze.
- Storage
- 4 °C
- Storage Comment
- Upon receipt store at 4°C. Stable for 6 months. Do not freeze.
- Expiry Date
- 6 months
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- Target
- CD31 (PECAM1) (Platelet/endothelial Cell Adhesion Molecule (PECAM1))
- Alternative Name
- CD31 (PECAM1 Products)
- Background
- CD31, also known as PECAM-1, is an adhesion molecule, which is expressed on endothelial cells at intercellular junctions and various T cell subsets. It is also found to be expressed on platelets, as well as most other leukocytes including monocytes and neutrophils. CD31 facilitates homotypic binding to itself, as well as heterotypic binding to the leukocyte integrins. CD31 plays a crucial role in facilitating the transendothelial migration of leukocytes through the intercellular junctions of vascular endothelial cells.
- Molecular Weight
- 82 kDa
- NCBI Accession
- NP_000433
- UniProt
- P16284
- Pathways
- Regulation of Actin Filament Polymerization
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