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Recombinant CD31 antibody (Extracellular Domain)

PECAM1 Reactivity: Human IF, IF/ICC, IF (p) Host: Alpaca Multiclonal 2MAC4-2PEC47-3MAC24-3MAC69-3MAC82-3PEC92 unconjugated single-domain Antibody (sdAb) Recombinant Antibody
Catalog No. ABIN7540324
  • Target See all CD31 (PECAM1) Antibodies
    CD31 (PECAM1) (Platelet/endothelial Cell Adhesion Molecule (PECAM1))
    Antibody Type
    Recombinant Antibody
    Fragment
    single-domain Antibody (sdAb)
    Binding Specificity
    • 16
    • 16
    • 15
    • 12
    • 9
    • 8
    • 7
    • 7
    • 7
    • 7
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Extracellular Domain
    Reactivity
    • 273
    • 141
    • 77
    • 62
    • 43
    • 31
    • 21
    • 20
    • 11
    • 7
    • 4
    • 4
    • 4
    • 1
    • 1
    • 1
    Human
    Host
    • 160
    • 155
    • 42
    • 7
    • 6
    • 3
    • 2
    Alpaca
    Expression System
    E.coli
    Clonality
    • 231
    • 136
    • 7
    • 1
    Multiclonal
    Conjugate
    • 172
    • 32
    • 30
    • 24
    • 13
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    This CD31 antibody is un-conjugated
    Application
    • 235
    • 196
    • 117
    • 108
    • 68
    • 44
    • 35
    • 33
    • 30
    • 26
    • 23
    • 19
    • 12
    • 12
    • 9
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Immunofluorescence (IF), Immunofluorescence (fixed cells) (IF/ICC), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Purpose
    Alpaca anti-human CD31 VHH is a carefully developed and validated nanobody (single-domain antibody) binding to human CD31 (PECAM-1) highly suitabe for tissue staining.
    Brand
    LIMAAbody®
    Specificity
    Detects endogenous levels of total human CD31 protein.
    Cross-Reactivity (Details)
    does not cross-react with mouse CD31 based on qualitative analysis
    Characteristics
    VHH protein tag: C-terminal (6x) His-Tag
    Purification
    Affinity-purified antibody fragment.
    Immunogen
    Recombinant protein containing the extracellular domain of murine CD31 protein.
    Clone
    2MAC4-2PEC47-3MAC24-3MAC69-3MAC82-3PEC92
    Top Product
    Discover our top product PECAM1 Primary Antibody
  • Application Notes
    Immunofluorescence: 10 μg/mL (frozen sections), 5 μg/mL (cell culture), 20 μg/mL (wholemount)
    Comment

    VHH protein tag: C-terminal (6x) His-Tag

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS, pH 7.4, 0.02% sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Do not freeze.
    Storage
    4 °C
    Storage Comment
    Upon receipt store at 4°C. Stable for 6 months. Do not freeze.
    Expiry Date
    6 months
  • Target
    CD31 (PECAM1) (Platelet/endothelial Cell Adhesion Molecule (PECAM1))
    Alternative Name
    CD31 (PECAM1 Products)
    Background
    CD31, also known as PECAM-1, is an adhesion molecule, which is expressed on endothelial cells at intercellular junctions and various T cell subsets. It is also found to be expressed on platelets, as well as most other leukocytes including monocytes and neutrophils. CD31 facilitates homotypic binding to itself, as well as heterotypic binding to the leukocyte integrins. CD31 plays a crucial role in facilitating the transendothelial migration of leukocytes through the intercellular junctions of vascular endothelial cells.
    Molecular Weight
    82 kDa
    NCBI Accession
    NP_000433
    UniProt
    P16284
    Pathways
    Regulation of Actin Filament Polymerization
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