CD160 antibody (FITC)

Catalog No. ABIN7540422

The Mouse Monoclonal anti-CD160 antibody has been validated for FACS. It is suitable to detect CD160 in samples from Human.

Quick Overview for CD160 antibody (FITC) (ABIN7540422)

Target: CD160

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD160 antibody is conjugated to FITC

Application: Flow Cytometry (FACS)

Clone: BY55

Product Details anti-CD160 Antibody (FITC)

Purpose: Anti-Hu CD160 FITC

Specificity: The mouse monoclonal antibody BY55 recognizes an extracellular epitope of CD160, a 27 kDa glycoprotein expressed on NK cells, NK-T cells, intestinal intraepithelial lymphocytes, TCR-gamma/delta T cells and a small population of TCR-alpha/beta T cells. The antibody detects both GPI-anchored and transmembrane form of CD160.

Purification: Purified antibody is conjugated with fluorescein isothiocyanate (FITC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

Immunogen: Human NK cell line YT2C2

Isotype: IgM kappa

Application Details

Application Notes: Flow cytometry: The reagent is designed for analysis of human blood cells using 4 μL reagent / 100 μL of whole blood or 10⁶ cells in a suspension. The content of a vial (0.4 ml) is sufficient for 100 tests.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Stabilizing Tris buffered saline (TBS), pH 8.0, 15 mM sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.

Target Details for CD160

Target: CD160

Alternative Name: CD160

Background:

NCBI Full Gene Name: CD160 Molecule

Description: CD160 is a cell surface glycoprotein of immunoglobulin superfamily, which functions as a costimulatory receptor expressed mainly on cytotoxic cell populations and recognizing both classical and non-classical MHC class I molecules. It can form disulfide-linked multimers. Down-modulation of CD160 occurs as a consequence of its proteolytic cleavage and the released soluble form was found to impair the MHC-class I specific cytotoxicity of CD8+ T lymphocytes and NK cells. In contrast to GPI-anchored isoform with broader expression among CD160 positive cells, expression of the transmembrane isoform is restricted to NK cells and is activation-dependent.

Other names: NK1, NK28

Gene name: CD160

Gene ID: 11126

UniProt: O95971