CD37 antibody (FITC)

Catalog No. ABIN7540442

This Mouse Monoclonal antibody specifically detects CD37 in FACS. It exhibits reactivity toward Human.

Quick Overview for CD37 antibody (FITC) (ABIN7540442)

Target: CD37 (TSPAN26) (Tetraspanin 26 (TSPAN26))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD37 antibody is conjugated to FITC

Application: Flow Cytometry (FACS)

Clone: MB-1

Product Details anti-CD37 Antibody (FITC)

Purpose: Anti-Hu CD37 FITC

Specificity: The mouse monoclonal antibody MB-1 recognizes an extracellular epitope of CD37, a tetraspanin family transmembrane glycoprotein.

Purification: Purified antibody is conjugated with fluorescein isothiocyanate (FITC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

Immunogen: lymphomatous lymph node cells

Isotype: IgG1 kappa

Application Details

Application Notes: Flow cytometry: The reagent is designed for analysis of human blood cells using 4 μL reagent / 100 μL of whole blood or 10⁶ cells in a suspension. The content of a vial (0.4 ml) is sufficient for 100 tests.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.

Target Details for CD37

Target: CD37 (TSPAN26) (Tetraspanin 26 (TSPAN26))

Alternative Name: CD37

Background:

NCBI Full Gene Name: CD37 Molecule

Description: CD37 is a 40-64 kDa tetraspanin family glycoprotein, which forms complexes in the B cell membrane with MHC class II, CD53, CD81, and CD82. It is expressed highly on mature B cells and neoplastic B cells, but it is lost on plasma cells, as well as on pro-B cells. Lower expression was detected on monocytes, macrophages, and dendritic cells.

Other names: GP52-40, tetraspanin 26

Gene name: CD37

Gene ID: 951

UniProt: P11049

Pathways: Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response