KLRF1 antibody (Extracellular Domain) (PE)

Catalog No. ABIN7540463

This Mouse Monoclonal antibody specifically detects KLRF1 in FACS. It exhibits reactivity toward Human and Monkey.

Quick Overview for KLRF1 antibody (Extracellular Domain) (PE) (ABIN7540463)

Target: KLRF1 (Killer Cell Lectin-Like Receptor Subfamily F, Member 1 (KLRF1))

Reactivity: Human, Monkey

Host: Mouse

Clonality: Monoclonal

Conjugate: This KLRF1 antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Clone: 5D12

Product Details anti-KLRF1 Antibody (PE)

Binding Specificity: Extracellular Domain

Purpose: Anti-Hu NKp80 PE

Specificity: The mouse monoclonal antibody 5D12 recognizes an extracellular epitope of human NKp80 (CLEC5C), a C-type lectin family member, expressed on NK cells and subsets of T cells.

No Cross-Reactivity: Mouse, Rat

Purification: Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

Immunogen: recombinant human NKp80 extracellular domain

Isotype: IgG1 kappa

Application Details

Application Notes: Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 10⁶ cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.

Target Details for KLRF1

Target: KLRF1 (Killer Cell Lectin-Like Receptor Subfamily F, Member 1 (KLRF1))

Alternative Name: NKp80

Background:

NCBI Full Gene Name: killer cell lectin like receptor F1

Description: NKp80, also known as CLEC5C or KLRF1, is a type II transmembrane glycoprotein of the C lectin family, which is expressed in 80 kDa homodimers on NK cells, and subsets of CD8+ alpha/beta T cells, and gamma/delta T cells. It belongs to the activating coreceptors, which induce cytotoxicity, and production of pro-inflammatory cytokines. Its ligand AICL is expressed on myeloid cells.

Other names: KLRF1, CLEC5C

Gene name: KLRF1

Gene ID: 51348

UniProt: Q9NZS2