PIK3R3 antibody (N-Term)
Quick Overview for PIK3R3 antibody (N-Term) (ABIN7540565)
Target
See all PIK3R3 AntibodiesReactivity
Host
Clonality
Conjugate
Application
-
-
Binding Specificity
- N-Term
-
Supplier Product No.
- 600-101-ml2
-
Supplier
- Rockland
-
Purpose
- Anti-PI3 Kinase p55 gamma Antibody
-
Cross-Reactivity (Details)
- This affinity purified antibody is directed against human PI 3 Kinase p55 gamma.
-
Purification
- The product was affinity purified from monospecific antiserum by immunoaffinity purification.
-
Sterility
- Sterile filtered
-
Immunogen
- Anti-PI3 Kinase p55 gamma antibody was prepared from whole goat serum produced by repeated immunizations with a synthetic peptide corresponding to a near N-Terminal portion of human PI3 Kinase p55 gamma conjugated to Keyhole Limpet Hemocyanin (KLH).
-
Isotype
- IgG
-
-
-
-
Application Notes
-
ELISA_Dilution: 1:10,000 - 50,000
Immunohistochemistry_Dilution: 1:100
IF_Microscopy_Dilution: 15 μg/mL
Western_Blot_Dilution: 1:1000
-
Comment
-
Anti-PI3 Kinase p55 gamma Antibody has been tested in WB, IF, and IHC. Expect bands ~44, 47, 54kDa in western blot using appropriate tissues or lysates. Positive control used: mouse testis in WB, A431 cells in IF, Human testis and Human tonsil tissue in IHC.
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Buffer
-
Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: None
Preservative: 0.01 % (w/v) Sodium Azide -
Preservative
- Sodium azide
-
Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Storage
- 4 °C,-20 °C
-
Storage Comment
- Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
-
Expiry Date
- 12 months
-
-
- PIK3R3 (Phosphatidylinositol 3-kinase regulatory subunit gamma (PIK3R3))
-
Alternative Name
- PIK3R3
-
Background
- Goat Anti-PI3 Kinase p55 gamma Antibody, Goat Anti-PIK3R3 Antibody, Anti-p55 gamma Antibody, Phosphoinositide-3-Kinase Regulatory Subunit 3, Phosphatidylinositol 3-Kinase 55 KDa Regulatory Subunit Gamma, Phosphoinositide-3-Kinase, Regulatory Subunit 3 (Gamma), PtdIns-3-Kinase Regulatory Subunit P55-Gamma, PI3-Kinase Regulatory Subunit Gamma, PI3K Regulatory Subunit Gamma, PI3-Kinase Subunit P55-Gamma, P55PIK, Phosphatidylinositol 3-Kinase, Regulatory Subunit, Polypeptide 3 (P55, Gamma), Phosphatidylinositol 3-Kinase Regulatory Subunit Gamma, Phosphoinositide-3-Kinase Regulatory Subunit Gamma, PtdIns-3-Kinase Regulatory Subunit Gamma, P55-GAMMA, P55,PI 3-Kinases (phosphoinositide 3-kinases, PI 3-Ks) are a family of lipid kinases capable of phosphorylating the 3'OH of the inositol ring of phosphoinositides. They are responsible for coordinating a diverse range of cell functions including proliferation and survival. PIK3R3 (Phosphoinositide-3-Kinase Regulatory Subunit 3) binds to activated (phosphorylated) protein-tyrosine kinases through its SH2 domain and regulates their kinase activity. During insulin stimulation, it also binds to IRS-1. Anti-PIK3R3 Antibody is useful for researchers interested in cancer research, Asbestos-related lung carcinomas, intravenous Leiomyomatosis, ERK signaling, and mTOR Pathways.
-
Gene ID
- 8503
-
NCBI Accession
- NP_001107644
-
UniProt
- Q92569
Target
-