HSV2 gD antibody

Catalog No. ABIN7540669

Supplier Product No.: mob542-01

The Mouse Monoclonal anti-HSV2 gD antibody (Clone DBM15-69) (ABIN7540669) specifically detects HSV2 gD in IHC. The antibody is reactive with Herpes Simplex Virus (HSV) samples.

Quick Overview for HSV2 gD antibody (ABIN7540669)

Target: HSV2 gD (Herpes Simplex Virus Type 2, Glycoprotein D (HSV2 gD))

Reactivity: Herpes Simplex Virus (HSV)

Host: Mouse

Clonality: Monoclonal

Conjugate: This HSV2 gD antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Clone: DBM15-69

Product Details anti-HSV2 gD Antibody

Supplier Product No.: mob542-01

Supplier: Rockland

Purpose: Herpes Simplex Virus Type II Monoclonal Antibody

Cross-Reactivity (Details): This antibody reacts with herpes simplex virus type 2.

Purification: The antibody is supplied as a purified immunoglobulin.

Immunogen: Anti-Herpes Simplex Virus Type II (HSV2) antibody was produced in BALB/C mice by repeated immunizations with Parker strain of herpes simplex virus type 2.

Isotype: IgG1

Application Details

Application Notes: Optional[Neutralization_Dilution]: 1:50-1:100

Comment:

Anti-Herpes Simplex Virus Type II (HSV2) (MOUSE) Monoclonal Antibody was tested with IHC-P positive control infected lung tissues. Cellular Localization: Cytoplasmic, nuclear. The user is advised to validate the use of the products with their tissue specimens prepared and handled in accordance with their laboratory practices. Consult references (Kiernan, 1981: Sheehan & Hrapchak, 1980) for further details on specimen preparation.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.01 % (w/v) Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store at 2-8°C. This antibody is suitable for use until the expiration date when stored at 2-8°C. Do not use product after the expiration date printed on vial. If reagents are stored under conditions other than those specified here, they must be verified by the user. Diluted reagents should be used promptly. Unused portions of antibody preparation should be discarded after one day. The presence of precipitate or an unusual odor indicates that the antibody is deteriorating and should not be used.

Target Details for HSV2 gD

Target: HSV2 gD (Herpes Simplex Virus Type 2, Glycoprotein D (HSV2 gD))

Alternative Name: HSV2 gD

Background: Herpes, Herpesvirus, Simplex, HSV, HSV2,Herpes simplex type 2 (HSV2) belongs to a family that includes HSV1, Epstein-Barr virus (EBV) and Varicella zoster (chicken pox) virus. HSV1 and HSV2 are extremely difficult to distinguish from each other. The HSV-1 strain generally appears in the orafacial organs. HSV2 usually resides in the sacral ganglion at the base of the spine. These viruses have a large DNA genome, capsid, and a lipid bilayer membrane derived from the nuclear membrane of the last host. These viruses are capable of entering a latent phase where the host shows no visible sign of infection. Envelope glycoprotein C (gC) and glycoprotein B (gB) bind to cell surface partials heparin sulfate. Receptor binding protein glycoprotein D (gD) binds to HVEM, nectin-1, and 3-O sulfated heparin sulfate forming complexes with glycoprotein H (gH) and glycoprotein (gL) creating an entry pore for the viral capsid.