Recombinant Complement Factor H antibody

Catalog No. ABIN7542937

This anti-Complement Factor H antibody is a Rabbit Chimeric antibody detecting Complement Factor H in WB, IP, ELISA and BR. Suitable for Human.

Quick Overview for Recombinant Complement Factor H antibody (ABIN7542937)

Target: Complement Factor H (CFH)

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Chimeric

Conjugate: This Complement Factor H antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), ELISA, Blocking Reagent (BR)

Clone: OX23

Product Details anti-Complement Factor H Antibody

Purpose: Anti-Factor H [OX23], Rabbit IgG, kappa

Specificity: This antibody binds to factor H, a cofactor in the inactication the complement cascade.

Cross-Reactivity: Mouse, Primate

Characteristics:

Original Species of Ab: Mouse

Original Format of Ab: IgG1

Purification: Protein A affinity purified

Immunogen: Native protein purified from plasma.

Isotype: IgG kappa

Application Details

Application Notes: This antibody binds to Factor H and has been used to determine Factor H levels in a sandwich ELISA assay (Daniels-Treffandier, 2016). Alone it has no effect on Factor H activity, but it is able to reduce the increase in cofactor activity mediated by the antibody clone OX24.

Comment:

This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Target Details for Complement Factor H

Target: Complement Factor H (CFH)

Alternative Name: Factor H

Background: CHF, AHUS1, AMBP1, ARMD4, ARMS1, CFHL3, FH, FHL1, HF, HF1, HF2, HUS, OX-23

UniProt: P08603

Pathways: Complement System, Cellular Response to Molecule of Bacterial Origin