Recombinant SIRPA antibody

Catalog No. ABIN7542991

This anti-SIRPA antibody is a Rabbit Chimeric antibody detecting SIRPA in WB, ELISA, IHC, IP, IF and Func. Suitable for Rat.

Quick Overview for Recombinant SIRPA antibody (ABIN7542991)

Target: SIRPA (Signal-Regulatory Protein alpha (SIRPA))

Antibody Type: Recombinant Antibody

Reactivity: Rat

Host: Rabbit

Clonality: Chimeric

Conjugate: This SIRPA antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunofluorescence (IF), Functional Studies (Func)

Clone: OX-41

Product Details anti-SIRPA Antibody

Purpose: Anti-CD172A/SIRPA [OX-41], Rabbit IgG, kappa

Specificity: This antibody binds to rat SIRP alpha, which is selectively expressed by myeloid and neuronal cells.

Characteristics:

Original Species of Ab: Mouse

Original Format of Ab: IgG2a

Purification: Protein A affinity purified

Immunogen: Rat resident peritoneal cells injected into BALB/c mice.

Isotype: IgG kappa

Application Details

Application Notes: This antibody binds to SIRP alpha, and can consequently be used to label neuronal cells and myeloid cells, namely macrophages, monocytes, granulocutes and dendritic cells, in immunofluorescence and immunohistochemical studies (Robinson, 1986). Anti-SIRP ligation induces nitric oxide synthesis and oxidative burst in macrophages (Adams, 1998).

Comment:

This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG2a format, for improved compatibility with existing reagents, assays and techniques.

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Target Details for SIRPA

Target: SIRPA (Signal-Regulatory Protein alpha (SIRPA))

Alternative Name: CD172A/SIRPA

Background: SIRPA, BIT, MFR, MYD-1, MYD1, P84, PTPNS1, SHPS1, SIRP, Signal-regulatory protein alpha, signal regulatory protein alpha, OX41, MRC OX-41, MRC OX 41

UniProt: P97710