Recombinant CD147 antibody

Catalog No. ABIN7543027

This anti-CD147 antibody is a Rabbit Chimeric antibody detecting CD147 in WB, FACS, IHC (fro) and RIA. Suitable for Rat.

Quick Overview for Recombinant CD147 antibody (ABIN7543027)

Target: CD147 (BSG) (Basigin (Ok Blood Group) (BSG))

Antibody Type: Recombinant Antibody

Reactivity: Rat

Host: Rabbit

Clonality: Chimeric

Conjugate: This CD147 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro)), Radioimmunoassay (RIA)

Clone: OX-47

Product Details anti-CD147 Antibody

Purpose: Anti-CD147 [OX-47], Rabbit IgG, kappa

Specificity: This antibody is specific for rat CD147, which has a broad distribution, OX-47 labels T and B cell blasts, peritoneal macrophages, the endothelium of all except large vessels and kidney tubules, but does not label TDL and thymocytes.

Characteristics:

Original Species of Ab: Mouse

Original Format of Ab: IgG1

Purification: Protein A affinity purified

Immunogen: Mice immunized with rat T blasts from a mixed lymphocyte reaction between purified CD4+ T cells and irradiated spleen cells.

Isotype: IgG kappa

Application Details

Application Notes: This antibody binds mouse CD147, and has been used in FC and IHC-fr analysis to characterise CD147 and detect the cell types on which it is expressed, indicating that CD147 is a lymphocyte activation marker (Paterson, 1987). This antibody failed to give immunoprecipitates from radiolabelled activated T cells.

Comment:

This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Target Details for CD147

Target: CD147 (BSG) (Basigin (Ok Blood Group) (BSG))

Alternative Name: CD147

Background: Basigin, BSG, extracellular matrix metalloproteinase inducer, EMMPRIN, Glycoprotein CE9, OX-47 antigen

UniProt: P26453

Pathways: S100 Proteins