Recombinant CD48 antibody
Quick Overview for Recombinant CD48 antibody (ABIN7543029)
Target
See all CD48 AntibodiesAntibody Type
Reactivity
Host
Clonality
Conjugate
Application
Clone
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Purpose
 - Anti-CD48 [OX-78], Rat IgG2a, kappa
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Specificity
 - OX-78 binds specifically to CD48 targets and labels mouse thymocytes, B and T cells and macrophages. CD48 is a CD2 ligand and may be involved in the facilitation of interactions between activated lymphocytes. This protein is also likely to be involved in T cell activation.
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Characteristics
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Original Species of Ab: Rat
Original Format of Ab: IgG2a
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Purification
 - Protein A affinity purified
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Immunogen
 - OX-78 was prepared by immunising rats against mouse CD48.
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Isotype
 - IgG2a kappa
 
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Application Notes
 - This antibody binds CD48, and has been used in immunoprecipitation and blocking studies to identify and characterise CD48, the ligand for murine CD2 (Kato, 1992). This antibody is able to block the binding of a chimeric molecule comprised of the extracellular domain of mouse CD2 and human IgG1 Fc to T cell lines at the ligand site.
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Restrictions
 - For Research Use only
 
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Concentration
 - 1 mg/mL
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Buffer
 - PBS with 0.02 % Proclin 300.
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Preservative
 - ProClin
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Precaution of Use
 - This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
 - 4 °C,-20 °C
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Storage Comment
 - Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
 
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- CD48
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Alternative Name
 - CD48
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Background
 - BCM1, BCM1 surface antigen, BLAST1, BLAST-1, HM48-1, MRC OX-45 surface antigen, MRC OX45 surface antigen, OX45 surface antigen, OX-45 surface antigen, SLAM family member 2, sgp60, sgp-60, OX78, MRC OX-78, MRC OX78
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UniProt
 - P18181
 
Target
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