Recombinant PDCD1LG2 antibody (Extracellular Domain)

Catalog No. ABIN7543103

This Mouse Monoclonal antibody specifically detects PDCD1LG2 in IHC. It exhibits reactivity toward Human.

Quick Overview for Recombinant PDCD1LG2 antibody (Extracellular Domain) (ABIN7543103)

Target: PDCD1LG2 (Programmed Cell Death 1 Ligand 2 (PDCD1LG2))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This PDCD1LG2 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Clone: 366C-9E5

Product Details anti-PDCD1LG2 Antibody

Binding Specificity: Extracellular Domain

Purpose: Anti-PD-L2 [366C.9E5], Mouse IgG1, kappa

Specificity: This antibody is specific for human PD-L2, and recognises an epitope in the IgV domain.

Characteristics:

Original Species of Ab: Mouse

Original Format of Ab: IgG1

Purification: Protein A affinity purified

Immunogen: This antibody was raised by immunising mice with a recombinant protein fragment corresponding to the extracellular domain of human PD-L2 (as an Ig fusion protein).

Isotype: IgG1 kappa

Application Details

Application Notes: This antibody has been used in the immunohistochemical detection of PD-L2 in formalin-fixed, paraffin-embedded tissue sections of Hodgkin's lymphoma tissue sections (Ansell et al, 2018, Roemer et al, 2016), primary mediastinal large B-cell lymphoma and diffuse large B-cell lymphoma biopsies (Shi et al, 2014, Chong et al, 2016), non-small-cell lung cancer tumour samples (Calles et al, 2015), primary and metastatic adenoid cystic carcinoma deposits (Sridharan et al, 2016), and tonsil and colorectal carcinoma tissue samples (Masugi et al, 2017).

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Target Details for PDCD1LG2

Target: PDCD1LG2 (Programmed Cell Death 1 Ligand 2 (PDCD1LG2))

Alternative Name: PD-L2

Background: CD273, Programmed cell death 1 ligand 2, PD-1 ligand 2, PDCD1 ligand 2, Programmed death ligand 2, Butyrophilin B7-DC, PDCD1LG2, B7DC, PDCD1L2, PD L2, 9E5

UniProt: Q9BQ51