Recombinant PDCD1LG2 antibody (Extracellular Domain)

Catalog No. ABIN7543104

The Rabbit Chimeric anti-PDCD1LG2 antibody has been validated for IHC. It is suitable to detect PDCD1LG2 in samples from Human.

Quick Overview for Recombinant PDCD1LG2 antibody (Extracellular Domain) (ABIN7543104)

Target: PDCD1LG2 (Programmed Cell Death 1 Ligand 2 (PDCD1LG2))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Chimeric

Conjugate: This PDCD1LG2 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Clone: 366C-9E5

Product Details anti-PDCD1LG2 Antibody

Binding Specificity: Extracellular Domain

Purpose: Anti-PD-L2 [366C.9E5], Rabbit IgG, kappa

Specificity: This antibody is specific for human PD-L2, and recognises an epitope in the IgV domain.

Characteristics:

Original Species of Ab: Mouse

Original Format of Ab: IgG1

Purification: Protein A affinity purified

Immunogen: This antibody was raised by immunising mice with a recombinant protein fragment corresponding to the extracellular domain of human PD-L2 (as an Ig fusion protein).

Isotype: IgG kappa

Application Details

Application Notes: This antibody has been used in the immunohistochemical detection of PD-L2 in formalin-fixed, paraffin-embedded tissue sections of Hodgkin's lymphoma tissue sections (Ansell et al, 2018, Roemer et al, 2016), primary mediastinal large B-cell lymphoma and diffuse large B-cell lymphoma biopsies (Shi et al, 2014, Chong et al, 2016), non-small-cell lung cancer tumour samples (Calles et al, 2015), primary and metastatic adenoid cystic carcinoma deposits (Sridharan et al, 2016), and tonsil and colorectal carcinoma tissue samples (Masugi et al, 2017).

Comment:

This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Target Details for PDCD1LG2

Target: PDCD1LG2 (Programmed Cell Death 1 Ligand 2 (PDCD1LG2))

Alternative Name: PD-L2

Background: CD273, Programmed cell death 1 ligand 2, PD-1 ligand 2, PDCD1 ligand 2, Programmed death ligand 2, Butyrophilin B7-DC, PDCD1LG2, B7DC, PDCD1L2, PD L2, 9E5

UniProt: Q9BQ51