Recombinant PD-L1 antibody

Catalog No. ABIN7543190

This Rabbit Chimeric antibody specifically detects PD-L1 in IHC and ELISA. It exhibits reactivity toward Human.

Quick Overview for Recombinant PD-L1 antibody (ABIN7543190)

Target: PD-L1 (CD274 (PD-L1))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Chimeric

Conjugate: This PD-L1 antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA

Clone: B7HC0013

Product Details anti-PD-L1 Antibody

Purpose: Anti-PD-L1 [B7HC0013], Rabbit IgG, kappa

Specificity: This antibody binds human PD-L1.

Characteristics:

Original Species of Ab: Mouse

Original Format of Ab: IgG1

Purification: Protein A affinity purified

Immunogen: The original antibody was generated by panning a naive human scfv library against decreasing concentrations of free recombinant human PD-L1 (his tagged).

Isotype: IgG kappa

Application Details

Application Notes: This antibody can bind human PD-L1 in an ELISA. It can also be used for immunohistochemical staining of PD-Ll over-expressing 'Clone 37' cell line (WO2014165082).

Comment:

This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Target Details for PD-L1

Target: PD-L1 (CD274 (PD-L1))

Alternative Name: PD-L1

Background: CD274, PDL1, B7-H1, B7H1, B7 homolog 1, hPD-L1, PDCD1L1, PDCD1LG1, PDCD1 ligand 1, Programmed cell death 1 ligand 1, Programmed death ligand 1

UniProt: Q9NZQ7

Pathways: Cancer Immune Checkpoints