Recombinant PD-L1 antibody

Catalog No. ABIN7543191

The Human Chimeric anti-PD-L1 antibody has been validated for FACS and IHC. It is suitable to detect PD-L1 in samples from Human.

Quick Overview for Recombinant PD-L1 antibody (ABIN7543191)

Target: PD-L1 (CD274 (PD-L1))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Human

Clonality: Chimeric

Conjugate: This PD-L1 antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunohistochemistry (IHC)

Clone: XGMHc25-1

Product Details anti-PD-L1 Antibody

Purpose: Anti-PD-L1 [XGMHc25.1], Human IgG1, kappa

Specificity: This antibody binds human PD-L1.

Characteristics:

Original Species of Ab: Mouse

Original Format of Ab: IgG2b

Purification: Protein A affinity purified

Immunogen: The original antibody was generated by immunizing BALB/c mice with a human B7-H1 fusion protein.

Isotype: IgG1 kappa

Application Details

Application Notes: This antibody is capable of binding B7-H1 Molecules expressed on the surface of M435 by flow cytometry. This antibody was also used for the immunohistochemical analysis of intestinal and gastric cancer tissues (WO2019085238)

Comment:

This chimeric human antibody was made using the variable domain sequences of the original Mouse IgG2b format, for improved compatibility with existing reagents, assays and techniques.

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Target Details for PD-L1

Target: PD-L1 (CD274 (PD-L1))

Alternative Name: PD-L1

Background: CD274, PDL1, B7-H1, B7H1, B7 homolog 1, hPD-L1, PDCD1L1, PDCD1LG1, PDCD1 ligand 1, Programmed cell death 1 ligand 1, Programmed death ligand 1

UniProt: Q9NZQ7

Pathways: Cancer Immune Checkpoints