Recombinant LI Cadherin antibody

Catalog No. ABIN7543348

This anti-LI Cadherin antibody is a Rabbit Chimeric antibody detecting LI Cadherin in ELISA and FACS. Suitable for Human.

Quick Overview for Recombinant LI Cadherin antibody (ABIN7543348)

Target: LI Cadherin

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Chimeric

Conjugate: This LI Cadherin antibody is un-conjugated

Application: ELISA, Flow Cytometry (FACS)

Clone: D2111

Product Details anti-LI Cadherin Antibody

Purpose: Anti-Cadherin 17 [D2111], Rabbit IgG, kappa

Specificity: This antibody recognizes the human cadherin 17. Cadherins are calcium-dependent cell adhesion proteins. It is localized on the surfaces of epithelial cells in regions of cell-cell contact known as adherens junctions. They preferentially interact with themselves in a homophilic manner in connecting cells, cadherins may thus contribute to the sorting of heterogeneous cell types.

Characteristics:

Original Species of Ab: Mouse

Original Format of Ab: IgG1

Purification: Protein A affinity purified

Immunogen: The original antibody was generated by immunizing GP64 transgenic mice with human cadherin 17.

Isotype: IgG kappa

Application Details

Application Notes: The binding characterization and epitope mapping of this antibody was done using ELISA. This antibody was capable of binding Huh6 cell line (liver cancer) and AGS cells (gastric cancer) in flow cytometry. Cu64 labelled version of this antibody was also used in the PET imaging of AGS transplant mice (JP2017024991).

Comment:

This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format for improved compatibility with existing reagents assays and techniques.

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Target Details for LI Cadherin

Target: LI Cadherin

Alternative Name: Cadherin 17

Background: Cadherin-17, CDH17, Intestinal peptide-associated transporter HPT-1, Liver-intestine cadherin, LI-cadherin

UniProt: Q12864