Recombinant Ferritin antibody
Quick Overview for Recombinant Ferritin antibody (ABIN7543449)
Target
See all Ferritin (FE) AntibodiesAntibody Type
Reactivity
Host
Clonality
Conjugate
Application
Clone
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Purpose
- Anti-Ferritin [F11 (HSF102)], Rabbit IgG, kappa
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Specificity
- This antibody binds human ferritin. This protein catalyzes the oxidation of ferrous iron(II) to ferric iron(III) and stores iron in a soluble, non-toxic, readily available form. Ferritin is important for iron homeostasis.
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Characteristics
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Original Species of Ab: Mouse
Original Format of Ab: IgG2a
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Purification
- Protein A affinity purified
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Immunogen
- The original antibody was generated by immunizing female Balb/c mice with ferritin extracted from human spleen cells.
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Isotype
- IgG kappa
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Application Notes
- The binding characterization of this antibody towards human spleen ferritin was done using ELISA. This antibody was also reported to show binding affinity for protein A. Binding of this antibody to ferritin causes antigen-induced conformational changes in the antibody and reduces its affinity for protein A (PMID: 9776583).
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Restrictions
- For Research Use only
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Concentration
- 1 mg/mL
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Buffer
- PBS with 0.02 % Proclin 300.
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Preservative
- ProClin
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Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C,-20 °C
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Storage Comment
- Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
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- Ferritin (FE)
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Alternative Name
- Ferritin
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Background
- FTMT, FTL, FTH1, Ferritin mitochondrial, B8
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UniProt
- Q8N4E7
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Pathways
- Transition Metal Ion Homeostasis
Target
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