Melatonin Receptor 1A antibody (AA 201-280)

Catalog No. ABIN723815

The Rabbit Polyclonal anti-Melatonin Receptor 1A antibody has been validated for WB, ELISA, FACS, IF (p), IHC (p), IHC (fro) and DB. It is suitable to detect Melatonin Receptor 1A in samples from Human, Mouse, Cow and Rat. There are 4+ publications available.

Quick Overview for Melatonin Receptor 1A antibody (AA 201-280) (ABIN723815)

Target: Melatonin Receptor 1A (MTNR1A)

Reactivity: Human, Mouse, Cow, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Melatonin Receptor 1A antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Dot Blot (DB)

Product Details anti-Melatonin Receptor 1A Antibody

Binding Specificity: AA 201-280

Cross-Reactivity: Cow, Human, Mouse, Rat

Predicted Reactivity: Dog,Cow,Sheep,Pig,Chicken,Guinea Pig

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human MTR-1A

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
dot-blot()

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-Melatonin Receptor 1A antibody (ABIN723815)

Yang, Tang, Wang, Zhang, Zan: "Melatonin promotes triacylglycerol accumulation via MT2 receptor during differentiation in bovine intramuscular preadipocytes." in: Scientific reports, Vol. 7, Issue 1, pp. 15080, (2019) (PubMed).

Tabecka-Lonczynska, Mytych, Solek, Kulpa, Koziorowski: "New insight on the role of melatonin receptors in reproductive processes of seasonal breeders on the example of mature male European bison (Bison bonasus, Linnaeus 1758)." in: Journal of photochemistry and photobiology. B, Biology, Vol. 173, pp. 84-91, (2017) (PubMed).

Jang, Na, Hong, Lee, Moon, Cho, Park, Lee, Chang, Lee, Ko, Lee, Choi: "Synergistic effect of melatonin and ghrelin in preventing cisplatin-induced ovarian damage via regulation of FOXO3a phosphorylation and binding to the p27Kip1promoter in primordial follicles." in: Journal of pineal research, Vol. 63, Issue 3, (2017) (PubMed).

Wang, Liu, Wu, Ma, Ahmad, Liu, Han, Jiang, Zhang, Yang: "Melatonin suppresses apoptosis and stimulates progesterone production by bovine granulosa cells via its receptors (MT1 and MT2)." in: Theriogenology, Vol. 78, Issue 7, pp. 1517-26, (2012) (PubMed).

Target Details for Melatonin Receptor 1A

Target: Melatonin Receptor 1A (MTNR1A)

Alternative Name: Melatonin Receptor 1A

Background:

Synonyms: MT1, MEL-1A-R, Melatonin receptor type 1A, Mel1a receptor, MTNR1A

Background: High affinity receptor for melatonin. Likely to mediates the reproductive and circadian actions of melatonin. The activity of this receptor is mediated by pertussis toxin sensitive G proteins that inhibit adenylate cyclase activity.

Gene ID: 4543

UniProt: P48039