ADNP antibody (AA 331-400) (HRP)

Catalog No. ABIN724049

The Rabbit Polyclonal anti-ADNP antibody is suitable to detect ADNP in samples from Mouse and Rat. It has been validated for WB, ELISA, IHC (p) and IHC (fro).

Quick Overview for ADNP antibody (AA 331-400) (HRP) (ABIN724049)

Target: ADNP (Activity-Dependent Neuroprotector Homeobox (ADNP))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ADNP antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-ADNP Antibody (HRP)

Binding Specificity: AA 331-400

Cross-Reactivity: Mouse, Rat

Predicted Reactivity: Human,Dog,Cow,Chicken

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ADNP

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for ADNP

Target: ADNP (Activity-Dependent Neuroprotector Homeobox (ADNP))

Alternative Name: ADNP

Background:

Synonyms: Activity dependent neuroprotective protein, Activity dependent neuroprotector, ADNP, NAP, KIAA0784

Background: The activity dependent neuroprotective protein (ADNP) gene is frequently amplified in many neoplasias, including breast, bladder, ovarian, pancreatic, and colon cancers. ADNP mRNA is abundantly expressed in distinct normal tissues, and high expression levels were encountered in malignant cells. ADNP is implicated in maintaining cell survival, perhaps through modulation of p53. The encoded protein contains one homeobox and nine zinc finger domains, suggesting that it functions as a transcription factor.

Gene ID: 23394

UniProt: Q9H2P0

Pathways: Regulation of Cell Size, Regulation of Carbohydrate Metabolic Process