CRP antibody

Catalog No. ABIN7565983

This Goat Polyclonal antibody specifically detects CRP in WB, ELISA, IHC and DB. It exhibits reactivity toward Human.

Quick Overview for CRP antibody (ABIN7565983)

Target: CRP (C-Reactive Protein (CRP))

Reactivity: Human

Host: Goat

Clonality: Polyclonal

Conjugate: This CRP antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Dot Blot (DB)

Product Details anti-CRP Antibody

Purpose: CRP Antibody

Cross-Reactivity (Details): Assay by immunoelectrophoresis resulted in a single precipitin arc against anti-Goat Serum as well as purified and partially purified Capsular Reactive Protein (CRP) [Human Serum].

Characteristics: Synonyms: goat anti-CRP Antibody, C reactive protein pentraxin related antibody, CRP antibody, MGC88244 antibody, PTX 1 antibody, PTX1 antibody

Purification: This product is an IgG fraction antibody purified from monospecific antiserum by a multi-step process which includes delipidation, salt fractionation and ion exchange chromatography followed by extensive dialysis against the buffer stated above.

Sterility: Sterile filtered

Immunogen:

Immunogen: Capsular Reactive Protein (CRP) [Human Serum]

Immunogen Type: Native Protein

Application Details

Application Notes: Application Note: Anti-CRP Antibody has been tested by dot blot and western blot and is suitable for ELISA and Immunohistochemistry. Specific conditions for reactivity should be optimized by the end user. Immunohistochemistry Dilution: 1:1,000-1:5,000 Western Blot Dilution: 1:2,000-1:10,000 ELISA Dilution: 1:4,000 - 1:40,000 Other: User Optimized

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer:

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Stabilizer: None

Preservative: 0.01 % (w/v) Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store vial at -20° C or below prior to opening. This vial contains a relatively low volume of reagent (25 μL). To minimize loss of volume dilute 1:10 by adding 225 μL of the buffer stated above directly to the vial. Recap, mix thoroughly and briefly centrifuge to collect the volume at the bottom of the vial. Use this intermediate dilution when calculating final dilutions as recommended below. Store the vial at -20°C or below after dilution. Avoid cycles of freezing and thawing.

Expiry Date: 12 months

Target Details for CRP

Target: CRP (C-Reactive Protein (CRP))

Alternative Name: CRP

Background: Background: CRP (C-Reactive Protein) belongs to the pentaxin family. It is involved in several host defense related functions based on its ability to recognize foreign pathogens and damaged cells of the host and to initiate their elimination by interacting with humoral and cellular effector systems in the blood. It promotes agglutination, bacterial capsular swelling, phagocytosis and complement fixation through its calcium-dependent binding to phosphorylcholine. Consequently, the level of this protein in plasma increases greatly during acute phase response to tissue injury, infection, or other inflammatory stimuli. CRP can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells. Diseases associated with CRP include Acute Pancreatitis and Appendicitis. Anti-CRP Antibody is ideal for researchers interested in cAMP Dependent PKA, IL6 signaling, calcium ion binding, and cholesterol binding.

Gene ID: 1401

NCBI Accession: NP_000558

UniProt: P02741

Pathways: Carbohydrate Homeostasis