SIGLEC9 antibody (APC)

Catalog No. ABIN7566525

Product Details anti-SIGLEC9 Antibody (APC)

Target: SIGLEC9 (Sialic Acid Binding Ig-Like Lectin 9 (SIGLEC9))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This SIGLEC9 antibody is conjugated to APC

Application: Flow Cytometry (FACS)

Purpose: APC Anti-Human CD329 Antibody[K8]

Clone: K8

Isotype: IgG1, kappa

Application Details

Application Notes: Each lot of this antibody is quality control tested by flow cytometric analysis. Applications vary, the appropriate dilutions must be determined for individual use.
FCM: 5 µL/test

Comment:

Matching Isotype Control: (ABIN7469762)

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Phosphate buffered solution, pH 7.2, containing 0.09 % stabilizer and 1 % protein protectant.

Storage: 4 °C

Storage Comment: This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.

Expiry Date: 12 months

Target Details for SIGLEC9

Target: SIGLEC9 (Sialic Acid Binding Ig-Like Lectin 9 (SIGLEC9))

Alternative Name: CD329 (SIGLEC9 Products)

Background: Siglec-9,Sialic acid-binding Ig-like lectin-9,Siglecs are cell surface receptors belonging to the immunoglobulin superfamily that recognize sugar antigens. The extracellular domain of siglec-9 contains an IgV region, which binds sialic acid, followed by two IgC regions. Siglec 9 and siglec 6-8,10-12 are CD33 (siglec 3) like siglecs, which have two ITIMs in the cytoplasmic tails, suggesting their functional involvement in signal transduction. It is highly expressed on neutrophils and monocytes, and at lower levels on the subpopulations of T and B lymphocytes and NK cells. Siglec-9 plays a role in negative regulation of T cell activation, and it also affects neutrophil apoptosis.

Gene ID: 27180

UniProt: Q9Y336