L-Selectin antibody (Elab Fluor®700)

Catalog No. ABIN7566703

This Rat Monoclonal antibody specifically detects L-Selectin in FACS. It exhibits reactivity toward Mouse.

Quick Overview for L-Selectin antibody (Elab Fluor®700) (ABIN7566703)

Target: L-Selectin (SELL) (Selectin L (SELL))

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This L-Selectin antibody is conjugated to Elab Fluor®700

Application: Flow Cytometry (FACS)

Clone: Mel14

Product Details anti-L-Selectin Antibody (Elab Fluor®700)

Purpose: Elab Fluor®700 Anti-Mouse CD62L Antibody[Mel14]

Isotype: IgG2a, kappa

Application Details

Application Notes: Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/10 cells in 100 μL volume].

Comment:

Matching Isotype Control: E-AB-F09833M1

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Phosphate buffered solution, pH 7.2, containing 0.09 % stabilizer and 1 % protein protectant.

Storage: 4 °C

Storage Comment: This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.

Expiry Date: 12 months

Target Details for L-Selectin

Target: L-Selectin (SELL) (Selectin L (SELL))

Alternative Name: CD62L

Background: CD62L,CD62 antigen-like family member L,L-selectin,LAM-1,LECAM1,Lnhr,Ly-22,Ly22,Lymph node homing receptor,Sell,CD62L is a 74-95 kD glycoprotein also known as L-selectin, LECAM-1, Ly-22, LAM-1, and MEL-14. It is a member of the selectin family and is expressed on the majority of B and naive T cells, a subset of memory T cells, monocytes, granulocytes, most thymocytes, and a subset of NK cells. CD62L is important in lymphocyte homing to high endothelial venules (HEV) in peripheral lymph nodes and leukocyte 'rolling' on activated endothelium. CD62L also contributes to neutrophil emigration at inflammatory sites. CD62L is rapidly shed from lymphocytes and neutrophils upon cellular activation and the expression levels of CD62L (in conjunction with other markers) have been used to distinguish naive, effector, and memory T cells. CD62L has been reported to interact with CD34, GlyCAM-1, and MAdCAM-1.

Gene ID: 20343

UniProt: P18337