SLAMF1 antibody (Elab Fluor®700)

Catalog No. ABIN7566907

This Rat Monoclonal antibody specifically detects SLAMF1 in FACS. It exhibits reactivity toward Mouse.

Quick Overview for SLAMF1 antibody (Elab Fluor®700) (ABIN7566907)

Target: SLAMF1 (Signaling Lymphocytic Activation Molecule Family Member 1 (SLAMF1))

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This SLAMF1 antibody is conjugated to Elab Fluor®700

Application: Flow Cytometry (FACS)

Clone: TC15-12F12-2

Product Details anti-SLAMF1 Antibody (Elab Fluor®700)

Purpose: Elab Fluor®700 Anti-Mouse CD150/SLAM Antibody[TC15-12F12.2]

Isotype: IgG2a, lambda

Application Details

Application Notes: Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/10 cells in 100 μL volume].

Comment:

Matching Isotype Control: E-AB-F09743M1

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Phosphate buffered solution, pH 7.2, containing 0.09 % stabilizer and 1 % protein protectant.

Storage: 4 °C

Storage Comment: This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.

Expiry Date: 12 months

Target Details for SLAMF1

Target: SLAMF1 (Signaling Lymphocytic Activation Molecule Family Member 1 (SLAMF1))

Alternative Name: CD150/SLAM

Background: CD 150,Signaling lymphocytic activation molecule,Slam,Slamf1,CD150 is a 75-95 kD member of the immunoglobulin superfamily, also known as SLAM (signaling lymphocyte activation molecule) or IPO-3. CD150, a single chain type I transmembrane molecule, is expressed on thymocytes, T cell subsets, B cells, dendritic cells, and endothelial cells. The expression is upregulated upon activation. CD150 expression has been shown to be maintained on Th1 but not Th2 clones. T regulatory cells express a relatively high level of CD150. Antibodies against CD150 have been shown to augment IFN-γ production by Th1 cells, especially when co-stimulated through the TCR. CD150 associates with the src homology 2-domain-containing protein tyrosine phosphatase SHP-2, and this association is thought to be involved in signal transduction. In combination with CD48, CD150 is a useful marker for hematopoietic stem cell studies.

Gene ID: 27218

UniProt: Q9QUM4