SERPINA1 antibody (AA 101-200)

Catalog No. ABIN724835

There is 1 publication for this product available. The Rabbit Polyclonal anti-SERPINA1 antibody is suitable to detect SERPINA1 in samples from Human, Rat and Mouse. It has been validated for ELISA, ICC, FACS, IHC (p), IF (cc), IF (p) and IHC (fro).

Quick Overview for SERPINA1 antibody (AA 101-200) (ABIN724835)

Target: SERPINA1 (serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 1 (SERPINA1))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SERPINA1 antibody is un-conjugated

Application: ELISA, Immunocytochemistry (ICC), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-SERPINA1 Antibody

Binding Specificity: AA 101-200

Cross-Reactivity: Human, Mouse, Rat

Predicted Reactivity: Dog,Cow,Pig

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human alpha 1 Antitrypsin

Isotype: IgG

Application Details

Application Notes: ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-SERPINA1 antibody (ABIN724835)

Feng, Yin, Ding, Yuan, Yang, Xu, Hu: "Alpha-1-antitrypsin suppresses oxidative stress in preeclampsia by inhibiting the p38MAPK signaling pathway: An in vivo and in vitro study." in: PLoS ONE, Vol. 12, Issue 3, pp. e0173711, (2017) (PubMed).

Target Details for SERPINA1

Target: SERPINA1 (serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 1 (SERPINA1))

Alternative Name: alpha 1 Antitrypsin

Background:

Synonyms: Tryptase, Alpha-1-Antitrypsin, alpha 1 Antitrypsin, A1A, A1AT, AAT, Alpha 1 antiproteinase, Alpha 1 antitrypsin, Alpha 1 protease inhibitor, alpha-1-AT, alpha1 PI, alpha1 proteinase inhibitor, Clade A alpha 1 antiproteinase antitrypsin member 1, MGC23330, MGC9222, PI, PI, PRO2275, Protease inhibitor 1 anti elastase, Serpin A1, Serpin peptidase inhibitor clade A alpha 1 antiproteinase antitrypsin member 1, SerpinA1, A1AT_HUMAN, Alpha-1-antitrypsin, Alpha-1 protease inhibitor, Alpha-1-antiproteinase, Serpin A1.

Background: Alpha-1-antitrypsin is a protease inhibitor, deficiency of which is associated with emphysema and liver disease. The protein is encoded by a gene (PI) located on the distal long arm of chromosome 14.

Gene ID: 5265