HSP70 antibody (AA 481-534) (Biotin)

Catalog No. ABIN725362

This Rabbit Polyclonal antibody specifically detects HSP70 in WB, ELISA, IHC (p) and IHC (fro). It exhibits reactivity toward Human, Mouse, Rat and Chicken.

Quick Overview for HSP70 antibody (AA 481-534) (Biotin) (ABIN725362)

Target: HSP70 (Heat Shock Protein 70 (HSP70))

Reactivity: Human, Mouse, Rat, Chicken

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HSP70 antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-HSP70 Antibody (Biotin)

Binding Specificity: AA 481-534

Cross-Reactivity: Chicken, Human, Mouse, Rat

Predicted Reactivity: Dog,Pig,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human HSP70

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for HSP70

Target: HSP70 (Heat Shock Protein 70 (HSP70))

Alternative Name: HSP70

Background:

Synonyms: HSP72, HSPA1, HSP7I, HSP7-1, HSP7-1A, HEL-S-13, Heat shock 7 kDa protein 1A/1B, Heat shock 7 kDa protein 1/2, HSP7-1/HSP7-2, HSP7.1/HSP7.2, HSPA1A, HSX7

Background: In cooperation with other chaperones, Hsp7s stabilize preexistent proteins against aggregation and mediate the folding of newly translated polypeptides in the cytosol as well as within organelles. These chaperones participate in all these processes through their ability to recognize nonnative conformations of other proteins. They bind extended peptide segments with a net hydrophobic character exposed by polypeptides during translation and membrane translocation, or following stress-induced damage. In case of rotavirus A infection, serves as a post-attachment receptor for the virus to facilitate entry into the cell.

Gene ID: 3303

UniProt: P08107