Recombinant MS4A1 (Rituximab Biosimilar) antibody

Catalog No. ABIN7581287

Product Details anti-MS4A1 (Rituximab Biosimilar) Antibody

Target: MS4A1 (Rituximab Biosimilar)

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Human

Expression System: CHO Cells

Clonality: Monoclonal

Conjugate: This MS4A1 (Rituximab Biosimilar) antibody is un-conjugated

Application: Flow Cytometry (FACS), ELISA, Bio-Layer Interferometry (BLI), Functional Studies (Func), Surface Plasmon Resonance (SPR)

Purpose: Anti-CD20 / MS4A1 Reference Antibody (rituximab)

Sequence: QVQLQQPGAE LVKPGASVKM SCKASGYTFT SYNMHWVKQT PGRGLEWIGA IYPGNGDTSY NQKFKGKATL TADKSSSTAY MQLSSLTSED SAVYYCARST YYGGDWYFNV WGAGTTVTVS AASTKGPSVF PLAPSSKSTS GGTAALGCLV KDYFPEPVTV SWNSGALTSG VHTFPAVLQS SGLYSLSSVV TVPSSSLGTQ TYICNVNHKP SNTKVDKKAE PKSCDKTHTC PPCPAPELLG GPSVFLFPPK PKDTLMISRT PEVTCVVVDV SHEDPEVKFN WYVDGVEVHN AKTKPREEQY NSTYRVVSVL TVLHQDWLNG KEYKCKVSNK ALPAPIEKTI SKAKGQPREP QVYTLPPSRD ELTKNQVSLT CLVKGFYPSD IAVEWESNGQ PENNYKTTPP VLDSDGSFFL YSKLTVDKSR WQQGNVFSCS VMHEALHNHY TQKSLSLSPG K,QIVLSQSPAI LSASPGEKVT MTCRASSSVS YIHWFQQKPG SSPKPWIYAT SNLASGVPVR FSGSGSGTSY SLTISRVEAE DAATYYCQQW TSNPPTFGGG TKLEIKRTVA APSVFIFPPS DEQLKSGTAS VVCLLNNFYP REAKVQWKVD NALQSGNSQE SVTEQDSKDS TYSLSSTLTL SKADYEKHKV YACEVTHQGL SSPVTKSFNR GEC

Characteristics: Anti-CD20 Reference Antibody (rituximab) is expressed from CHO. The heavy chain type is huIgG1, and the light chain type is hukappa. It has a predicted MW of 146.32 kDa.

Purity: >95 %

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

Therapeutic Agents by Target and Mechanism: CD20 inhibitors(B lymphocyte antigen CD20 inhibitors), ADCC(antibody-dependent cytotoxicity), CD20(targeted cytolysis)

Conditions: Chronic Lymphocytic Leukemia Non-Hodgkin's Lymphoma Rheumatoid Arthritis (Anti-TNF Refractory) Vasculitis ANCA-associated

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: 1 mg/mL

Buffer: 25 mM histidine, 8 % sucrose, 0.01 % Tween80 pH 6.2

Storage: 4 °C,-80 °C

Storage Comment: +4°C,-80°C

Target Details for MS4A1 (Rituximab Biosimilar)

Target: MS4A1 (Rituximab Biosimilar)

Alternative Name: CD20 (Rituximab Biosimilar) (MS4A1 (Rituximab Biosimilar) Products)

Target Type: Biosimilar

Background: Synonyms: Membrane-spanning 4-domains, subfamily A, member 1, MS4A1, B lymphocyte surface antigen B1, Leu-16, Bp35

Molecular Weight: 146.32 kDa

UniProt: P11836