Recombinant CD52 (Alemtuzumab Biosimilar) antibody
Reactivity: Human
FACS, ELISA, SPR, Func, BLI
Host: Human
Monoclonal
unconjugated
Recombinant Antibody
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- Target See all CD52 (Alemtuzumab Biosimilar) products
- CD52 (Alemtuzumab Biosimilar)
- Antibody Type
- Recombinant Antibody
- Reactivity
- Human
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Host
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Human
- Expression System
- CHO Cells
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Clonality
- Monoclonal
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Conjugate
- This CD52 (Alemtuzumab Biosimilar) antibody is un-conjugated
- Application
- Flow Cytometry (FACS), ELISA, Surface Plasmon Resonance (SPR), Functional Studies (Func), Bio-Layer Interferometry (BLI)
- Purpose
- Anti-CD52 Reference Antibody (alemtuzumab)
- Sequence
- QVQLQESGPG LVRPSQTLSL TCTVSGFTFT DFYMNWVRQP PGRGLEWIGF IRDKAKGYTT EYNPSVKGRV TMLVDTSKNQ FSLRLSSVTA ADTAVYYCAR EGHTAAPFDY WGQGSLVTVS SASTKGPSVF PLAPSSKSTS GGTAALGCLV KDYFPEPVTV SWNSGALTSG VHTFPAVLQS SGLYSLSSVV TVPSSSLGTQ TYICNVNHKP SNTKVDKKVE PKSCDKTHTC PPCPAPELLG GPSVFLFPPK PKDTLMISRT PEVTCVVVDV SHEDPEVKFN WYVDGVEVHN AKTKPREEQY NSTYRVVSVL TVLHQDWLNG KEYKCKVSNK ALPAPIEKTI SKAKGQPREP QVYTLPPSRD ELTKNQVSLT CLVKGFYPSD IAVEWESNGQ PENNYKTTPP VLDSDGSFFL YSKLTVDKSR WQQGNVFSCS VMHEALHNHY TQKSLSLSPG K,DIQMTQSPSS LSASVGDRVT ITCKASQNID KYLNWYQQKP GKAPKLLIYN TNNLQTGVPS RFSGSGSGTD FTFTISSLQP EDIATYYCLQ HISRPRTFGQ GTKVEIKRTV AAPSVFIFPP SDEQLKSGTA SVVCLLNNFY PREAKVQWKV DNALQSGNSQ ESVTEQDSKD STYSLSSTLT LSKADYEKHK VYACEVTHQG LSSPVTKSFN RGEC
- Characteristics
- Anti-CD52 Reference Antibody (alemtuzumab) is expressed from CHO. The heavy chain type is huIgG1, and the light chain type is hukappa. It has a predicted MW of 145.5 kDa.
- Purity
- >95 %
- Isotype
- IgG1
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Comment
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Therapeutic Agents by Target and Mechanism: CD52 inhibitors, ADCC, complement-dependent cytotoxicity
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Concentration
- 1 mg/mL
- Buffer
- 25 mM histidine, 8 % sucrose, 0.01 % Tween80 pH 6.2
- Storage
- 4 °C,-80 °C
- Storage Comment
- +4°C,-80°C
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- Target
- CD52 (Alemtuzumab Biosimilar)
- Abstract
- CD52 (Alemtuzumab Biosimilar) Products
- Target Type
- Biosimilar
- Molecular Weight
- 145.5 kDa
- UniProt
- P31358
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