Recombinant CLDN18.2 (Zolbetuximab Biosimilar) antibody

Catalog No. ABIN7581329

This anti-CLDN18.2 (Zolbetuximab Biosimilar) antibody is a Human Monoclonal antibody detecting CLDN18.2 (Zolbetuximab Biosimilar) in FACS, BLI, ELISA, Func and SPR. Suitable for Human.

Quick Overview for Recombinant CLDN18.2 (Zolbetuximab Biosimilar) antibody (ABIN7581329)

Target: CLDN18.2 (Zolbetuximab Biosimilar)

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Human

Clonality: Monoclonal

Conjugate: This CLDN18.2 (Zolbetuximab Biosimilar) antibody is un-conjugated

Application: Flow Cytometry (FACS), Bio-Layer Interferometry (BLI), ELISA, Functional Studies (Func), Surface Plasmon Resonance (SPR)

Product Details anti-CLDN18.2 (Zolbetuximab Biosimilar) Antibody

Expression System: CHO Cells

Purpose: Anti-CLDN18.2 Reference Antibody (zolbetuximab)

Sequence: QVQLQQPGAE LVRPGASVKL SCKASGYTFT SYWINWVKQR PGQGLEWIGN IYPSDSYTNY NQKFKDKATL TVDKSSSTAY MQLSSPTSED SAVYYCTRSW RGNSFDYWGQ GTTLTVSSAS TKGPSVFPLA PSSKSTSGGT AALGCLVKDY FPEPVTVSWN SGALTSGVHT FPAVLQSSGL YSLSSVVTVP SSSLGTQTYI CNVNHKPSNT KVDKRVEPKS CDKTHTCPPC PAPELLGGPS VFLFPPKPKD TLMISRTPEV TCVVVDVSHE DPEVKFNWYV DGVEVHNAKT KPREEQYNST YRVVSVLTVL HQDWLNGKEY KCKVSNKALP APIEKTISKA KGQPREPQVY TLPPSREEMT KNQVSLTCLV KGFYPSDIAV EWESNGQPEN NYKTTPPVLD SDGSFFLYSK LTVDKSRWQQ GNVFSCSVMH EALHNHYTQK SLSLSPGK,DIVMTQSPSS LTVTAGEKVT MSCKSSQSLL NSGNQKNYLT WYQQKPGQPP KLLIYWASTR ESGVPDRFTG SGSGTDFTLT ISSVQAEDLA VYYCQNDYSY PFTFGSGTKL EIKRTVAAPS VFIFPPSDEQ LKSGTASVVC LLNNFYPREA KVQWKVDNAL QSGNSQESVT EQDSKDSTYS LSSTLTLSKA DYEKHKVYAC EVTHQGLSSP VTKSFNRGEC

Characteristics: Anti-CLDN18.2 Reference Antibody (zolbetuximab) is expressed from CHO. The heavy chain type is huIgG1, and the light chain type is hukappa. It has a predicted MW of 145.5 kDa.

Purity: >95 %

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

Therapeutic Agents by Target and Mechanism: CLDN18.2 inhibitors, ADCC, complement-dependent cytotoxicity

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: 1 mg/mL

Buffer: 25 mM histidine, 8 % sucrose, 0.01 % Tween80 pH 6.2

Storage: 4 °C,-80 °C

Storage Comment: +4°C,-80°C

Target Details for CLDN18.2 (Zolbetuximab Biosimilar)

Target: CLDN18.2 (Zolbetuximab Biosimilar)

Target Type: Biosimilar

Molecular Weight: 145.5 kDa

UniProt: P56856