Recombinant CLDN18.2 (Zolbetuximab Biosimilar) antibody
Reactivity: Human
FACS, BLI, ELISA, Func, SPR
Host: Human
Monoclonal
unconjugated
Recombinant Antibody
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- Target See all CLDN18.2 (Zolbetuximab Biosimilar) products
- CLDN18.2 (Zolbetuximab Biosimilar)
- Antibody Type
- Recombinant Antibody
- Reactivity
- Human
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Host
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Human
- Expression System
- CHO Cells
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Clonality
- Monoclonal
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Conjugate
- This CLDN18.2 (Zolbetuximab Biosimilar) antibody is un-conjugated
- Application
- Flow Cytometry (FACS), Bio-Layer Interferometry (BLI), ELISA, Functional Studies (Func), Surface Plasmon Resonance (SPR)
- Purpose
- Anti-CLDN18.2 Reference Antibody (zolbetuximab)
- Sequence
- QVQLQQPGAE LVRPGASVKL SCKASGYTFT SYWINWVKQR PGQGLEWIGN IYPSDSYTNY NQKFKDKATL TVDKSSSTAY MQLSSPTSED SAVYYCTRSW RGNSFDYWGQ GTTLTVSSAS TKGPSVFPLA PSSKSTSGGT AALGCLVKDY FPEPVTVSWN SGALTSGVHT FPAVLQSSGL YSLSSVVTVP SSSLGTQTYI CNVNHKPSNT KVDKRVEPKS CDKTHTCPPC PAPELLGGPS VFLFPPKPKD TLMISRTPEV TCVVVDVSHE DPEVKFNWYV DGVEVHNAKT KPREEQYNST YRVVSVLTVL HQDWLNGKEY KCKVSNKALP APIEKTISKA KGQPREPQVY TLPPSREEMT KNQVSLTCLV KGFYPSDIAV EWESNGQPEN NYKTTPPVLD SDGSFFLYSK LTVDKSRWQQ GNVFSCSVMH EALHNHYTQK SLSLSPGK,DIVMTQSPSS LTVTAGEKVT MSCKSSQSLL NSGNQKNYLT WYQQKPGQPP KLLIYWASTR ESGVPDRFTG SGSGTDFTLT ISSVQAEDLA VYYCQNDYSY PFTFGSGTKL EIKRTVAAPS VFIFPPSDEQ LKSGTASVVC LLNNFYPREA KVQWKVDNAL QSGNSQESVT EQDSKDSTYS LSSTLTLSKA DYEKHKVYAC EVTHQGLSSP VTKSFNRGEC
- Characteristics
- Anti-CLDN18.2 Reference Antibody (zolbetuximab) is expressed from CHO. The heavy chain type is huIgG1, and the light chain type is hukappa. It has a predicted MW of 145.5 kDa.
- Purity
- >95 %
- Isotype
- IgG1
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Comment
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Therapeutic Agents by Target and Mechanism: CLDN18.2 inhibitors, ADCC, complement-dependent cytotoxicity
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Concentration
- 1 mg/mL
- Buffer
- 25 mM histidine, 8 % sucrose, 0.01 % Tween80 pH 6.2
- Storage
- 4 °C,-80 °C
- Storage Comment
- +4°C,-80°C
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- Target
- CLDN18.2 (Zolbetuximab Biosimilar)
- Abstract
- CLDN18.2 (Zolbetuximab Biosimilar) Products
- Target Type
- Biosimilar
- Molecular Weight
- 145.5 kDa
- UniProt
- P56856
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