Recombinant DLL3 (Rovalpituzumab Biosimilar) antibody
Reactivity: Human
FACS, SPR, Func, ELISA, BLI
Host: Human
Monoclonal
unconjugated
Recombinant Antibody
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- Target See all DLL3 (Rovalpituzumab Biosimilar) products
- DLL3 (Rovalpituzumab Biosimilar)
- Antibody Type
- Recombinant Antibody
- Reactivity
- Human
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Host
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Human
- Expression System
- CHO Cells
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Clonality
- Monoclonal
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Conjugate
- This DLL3 (Rovalpituzumab Biosimilar) antibody is un-conjugated
- Application
- Flow Cytometry (FACS), Surface Plasmon Resonance (SPR), Functional Studies (Func), ELISA, Bio-Layer Interferometry (BLI)
- Purpose
- Anti-DLL3 Reference Antibody (rovalpituzumab)
- Sequence
- QVQLVQSGAE VKKPGASVKV SCKASGYTFT NYGMNWVRQA PGQGLEWMGW INTYTGEPTY ADDFKGRVTM TTDTSTSTAY MELRSLRSDD TAVYYCARIG DSSPSDYWGQ GTLVTVSSAS TKGPSVFPLA PSSKSTSGGT AALGCLVKDY FPEPVTVSWN SGALTSGVHT FPAVLQSSGL YSLSSVVTVP SSSLGTQTYI CNVNHKPSNT KVDKKVEPKS CDKTHTCPPC PAPELLGGPS VFLFPPKPKD TLMISRTPEV TCVVVDVSHE DPEVKFNWYV DGVEVHNAKT KPREEQYNST YRVVSVLTVL HQDWLNGKEY KCKVSNKALP APIEKTISKA KGQPREPQVY TLPPSRDELT KNQVSLTCLV KGFYPSDIAV EWESNGQPEN NYKTTPPVLD SDGSFFLYSK LTVDKSRWQQ GNVFSCSVMH EALHNHYTQK SLSLSPG,EIVMTQSPAT LSVSPGERAT LSCKASQSVS NDVVWYQQKP GQAPRLLIYY ASNRYTGIPA RFSGSGSGTE FTLTISSLQS EDFAVYYCQQ DYTSPWTFGQ GTKLEIKRTV AAPSVFIFPP SDEQLKSGTA SVVCLLNNFY PREAKVQWKV DNALQSGNSQ ESVTEQDSKD STYSLSSTLT LSKADYEKHK VYACEVTHQG LSSPVTKSFN RGEC
- Characteristics
- Anti-DLL3 Reference Antibody (rovalpituzumab) is expressed from CHO. The heavy chain type is huIgG1, and the light chain type is hukappa. It has a predicted MW of 145.5 kDa.
- Purity
- >95 %
- Isotype
- IgG1
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Comment
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Therapeutic Agents by Target and Mechanism: DLL3 inhibitors
Conditions: Cancer Lung Cancer (advanced small cell)
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Concentration
- 1 mg/mL
- Buffer
- 25 mM histidine, 8 % sucrose, 0.01 % Tween80 pH 6.2
- Storage
- 4 °C,-80 °C
- Storage Comment
- +4°C,-80°C
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- Target
- DLL3 (Rovalpituzumab Biosimilar)
- Abstract
- DLL3 (Rovalpituzumab Biosimilar) Products
- Target Type
- Biosimilar
- Background
- Synonyms: Delta Like Canonical Notch Ligand 3, D3
- Molecular Weight
- 145.5 kDa
- UniProt
- Q9NYJ7
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