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Recombinant ErbB3 (Lumretuzumab Biosimilar) antibody

This Human Monoclonal antibody specifically detects ErbB3 (Lumretuzumab Biosimilar) in ELISA, BLI, FACS, Func and SPR. It exhibits reactivity toward Human.
Catalog No. ABIN7675979
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Quick Overview for Recombinant ErbB3 (Lumretuzumab Biosimilar) antibody (ABIN7675979)

Target

ErbB3 (Lumretuzumab Biosimilar)

Antibody Type

Recombinant Antibody

Reactivity

Human

Host

  • 1
  • 1
Human

Clonality

  • 1
  • 1
Monoclonal

Conjugate

  • 2
This ErbB3 (Lumretuzumab Biosimilar) antibody is un-conjugated

Application

ELISA, Bio-Layer Interferometry (BLI), Flow Cytometry (FACS), Functional Studies (Func), Surface Plasmon Resonance (SPR)
  • Expression System

    CHO Cells

    Purpose

    Anti-ERBB3 / HER3 Reference Antibody (lumretuzumab)

    Sequence

    QVQLVQSGAE VKKPGASVKV SCKASGYTFR SSYISWVRQA PGQGLEWMGW IYAGTGSPSY NQKLQGRVTM TTDTSTSTAY MELRSLRSDD TAVYYCARHR DYYSNSLTYW GQGTLVTVSS ASTKGPSVFP LAPSSKSTSG GTAALGCLVK DYFPEPVTVS WNSGALTSGV HTFPAVLQSS GLYSLSSVVT VPSSSLGTQT YICNVNHKPS NTKVDKKVEP KSCDKTHTCP PCPAPELLGG PSVFLFPPKP KDTLMISRTP EVTCVVVDVS HEDPEVKFNW YVDGVEVHNA KTKPREEQYN STYRVVSVLT VLHQDWLNGK EYKCKVSNKA LPAPIEKTIS KAKGQPREPQ VYTLPPSRDE LTKNQVSLTC LVKGFYPSDI AVEWESNGQP ENNYKTTPPV LDSDGSFFLY SKLTVDKSRW QQGNVFSCSV MHEALHNHYT QKSLSLSPG,DIVMTQSPDS LAVSLGERAT INCKSSQSVL NSGNQKNYLT WYQQKPGQPP KLLIYWASTR ESGVPDRFSG SGSGTDFTLT ISSLQAEDVA VYYCQSDYSY PYTFGQGTKL EIKRTVAAPS VFIFPPSDEQ LKSGTASVVC LLNNFYPREA KVQWKVDNAL QSGNSQESVT EQDSKDSTYS LSSTLTLSKA DYEKHKVYAC EVTHQGLSSP VTKSFNRGEC

    Characteristics

    Anti-ERBB3 / HER3 Reference Antibody (lumretuzumab) is expressed from CHO. The heavy chain type is huIgG1, and the light chain type is hukappa. It has a predicted MW of 145.5 kDa.

    Purity

    >95 %

    Isotype

    IgG1
  • Application Notes

    Optimal working dilution should be determined by the investigator.

    Comment

    Therapeutic Agents by Target and Mechanism: HER3 antagonist

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Concentration

    1 mg/mL

    Buffer

    25 mM histidine, 8 % sucrose, 0.01 % Tween80 pH 6.2

    Storage

    4 °C,-80 °C

    Storage Comment

    +4°C,-80°C
  • Target

    ErbB3 (Lumretuzumab Biosimilar)

    Target Type

    Biosimilar

    Molecular Weight

    145.5 kDa

    UniProt

    P21860
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