Recombinant FGFR2 (Bemarituzumab Biosimilar) antibody
Quick Overview for Recombinant FGFR2 (Bemarituzumab Biosimilar) antibody (ABIN7581408)
Target
Antibody Type
Reactivity
Host
Clonality
Conjugate
Application
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Expression System
- CHO Cells
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Purpose
- Anti-FGFR2 / CD332 Reference Antibody (bemarituzumab)
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Sequence
- QVQLVQSGAE VKKPGSSVKV SCKASGYIFT TYNVHWVRQA PGQGLEWIGS IYPDNGDTSY NQNFKGRATI TADKSTSTAY MELSSLRSED TAVYYCARGD FAYWGQGTLV TVSSASTKGP SVFPLAPSSK STSGGTAALG CLVKDYFPEP VTVSWNSGAL TSGVHTFPAV LQSSGLYSLS SVVTVPSSSL GTQTYICNVN HKPSNTKVDK RVEPKSCDKT HTCPPCPAPE LLGGPSVFLF PPKPKDTLMI SRTPEVTCVV VDVSHEDPEV KFNWYVDGVE VHNAKTKPRE EQYNSTYRVV SVLTVLHQDW LNGKEYKCKV SNKALPAPIE KTISKAKGQP REPQVYTLPP SREEMTKNQV SLTCLVKGFY PSDIAVEWES NGQPENNYKT TPPVLDSDGS FFLYSKLTVD KSRWQQGNVF SCSVMHEALH NHYTQKSLSL SPGK,DIQMTQSPSS LSASVGDRVT ITCKASQGVS NDVAWYQQKP GKAPKLLIYS ASYRYTGVPS RFSGSGSGTD FTFTISSLQP EDIATYYCQQ HSTTPYTFGQ GTKLEIKRTV AAPSVFIFPP SDEQLKSGTA SVVCLLNNFY PREAKVQWKV DNALQSGNSQ ESVTEQDSKD STYSLSSTLT LSKADYEKHK VYACEVTHQG LSSPVTKSFN RGEC
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Characteristics
- Anti-FGFR2 / CD332 Reference Antibody (bemarituzumab) is expressed from CHO. The heavy chain type is huIgG1, and the light chain type is hukappa. It has a predicted MW of 145.24 kDa.
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Purity
- >95 %
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Isotype
- IgG1
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Comment
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Therapeutic Agents by Target and Mechanism: FGFR2 antagonist
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Concentration
- 1 mg/mL
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Buffer
- 25 mM histidine, 8 % sucrose, 0.01 % Tween80 pH 6.2
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Storage
- 4 °C,-80 °C
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Storage Comment
- +4°C,-80°C
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- FGFR2 (Bemarituzumab Biosimilar)
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Target Type
- Biosimilar
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Molecular Weight
- 145.24 kDa
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UniProt
- P21802
Target
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