Recombinant GPC3 (Codrituzumab Biosimilar) antibody

Catalog No. ABIN7581429

This Human Monoclonal antibody specifically detects GPC3 (Codrituzumab Biosimilar) in ELISA, FACS, BLI, Func and SPR. It exhibits reactivity toward Human.

Quick Overview for Recombinant GPC3 (Codrituzumab Biosimilar) antibody (ABIN7581429)

Target: GPC3 (Codrituzumab Biosimilar)

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Human

Clonality: Monoclonal

Conjugate: This GPC3 (Codrituzumab Biosimilar) antibody is un-conjugated

Application: ELISA, Flow Cytometry (FACS), Bio-Layer Interferometry (BLI), Functional Studies (Func), Surface Plasmon Resonance (SPR)

Product Details anti-GPC3 (Codrituzumab Biosimilar) Antibody

Expression System: CHO Cells

Purpose: Anti-GPC3 / Glypican-3 Reference Antibody (codrituzumab)

Sequence: QVQLVQSGAE VKKPGASVKV SCKASGYTFT DYEMHWVRQA PGQGLEWMGA LDPKTGDTAY SQKFKGRVTL TADKSTSTAY MELSSLTSED TAVYYCTRFY SYTYWGQGTL VTVSSASTKG PSVFPLAPSS KSTSGGTAAL GCLVKDYFPE PVTVSWNSGA LTSGVHTFPA VLQSSGLYSL SSVVTVPSSS LGTQTYICNV NHKPSNTKVD KKVEPKSCDK THTCPPCPAP ELLGGPSVFL FPPKPKDTLM ISRTPEVTCV VVDVSHEDPE VKFNWYVDGV EVHNAKTKPR EEQYNSTYRV VSVLTVLHQD WLNGKEYKCK VSNKALPAPI EKTISKAKGQ PREPQVYTLP PSRDELTKNQ VSLTCLVKGF YPSDIAVEWE SNGQPENNYK TTPPVLDSDG SFFLYSKLTV DKSRWQQGNV FSCSVMHEAL HNHYTQKSLS LSPGK,DVVMTQSPLS LPVTPGEPAS ISCRSSQSLV HSNRNTYLHW YLQKPGQSPQ LLIYKVSNRF SGVPDRFSGS GSGTDFTLKI SRVEAEDVGV YYCSQNTHVP PTFGQGTKLE IKRTVAAPSV FIFPPSDEQL KSGTASVVCL LNNFYPREAK VQWKVDNALQ SGNSQESVTE QDSKDSTYSL SSTLTLSKAD YEKHKVYACE VTHQGLSSPV TKSFNRGEC

Characteristics: Anti-GPC3 / Glypican-3 Reference Antibody (codrituzumab) is expressed from CHO. The heavy chain type is huIgG1, and the light chain type is hukappa. It has a predicted MW of 145.5 kDa.

Purity: >95 %

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

Therapeutic Agents by Target and Mechanism: GPC3 inhibitors, ADCC, Antibody-dependent phagocytosis

Conditions: Liver Cancer  

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: 1 mg/mL

Buffer: 25 mM histidine, 8 % sucrose, 0.01 % Tween80 pH 6.2

Storage: 4 °C,-80 °C

Storage Comment: +4°C,-80°C

Target Details for GPC3 (Codrituzumab Biosimilar)

Target: GPC3 (Codrituzumab Biosimilar)

Target Type: Biosimilar

Background: Synonyms: GPC3

Molecular Weight: 145.5 kDa

UniProt: P51654