Recombinant ICOS (Vopratelimab Biosimilar) antibody
Reactivity: Human
ELISA, FACS, BLI, Func, SPR
Host: Human
Monoclonal
unconjugated
Recombinant Antibody
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- Target See all ICOS (Vopratelimab Biosimilar) products
- ICOS (Vopratelimab Biosimilar)
- Antibody Type
- Recombinant Antibody
- Reactivity
- Human
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Host
-
Human
- Expression System
- CHO Cells
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Clonality
- Monoclonal
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Conjugate
- This ICOS (Vopratelimab Biosimilar) antibody is un-conjugated
- Application
- ELISA, Flow Cytometry (FACS), Bio-Layer Interferometry (BLI), Functional Studies (Func), Surface Plasmon Resonance (SPR)
- Purpose
- Anti-ICOS / CD278 Reference Antibody (vopratelimab)
- Sequence
- EVQLVESGGG LVQPGGSLRL SCAASGFTFS DYWMDWVRQA PGKGLVWVSN IDEDGSITEY SPFVKGRFTI SRDNAKNTLY LQMNSLRAED TAVYYCTRWG RFGFDSWGQG TLVTVSSAST KGPSVFPLAP SSKSTSGGTA ALGCLVKDYF PEPVTVSWNS GALTSGVHTF PAVLQSSGLY SLSSVVTVPS SSLGTQTYIC NVNHKPSNTK VDKKVEPKSC DKTHTCPPCP APELLGGPSV FLFPPKPKDT LMISRTPEVT CVVVDVSHED PEVKFNWYVD GVEVHNAKTK PREEQYNSTY RVVSVLTVLH QDWLNGKEYK CKVSNKALPA PIEKTISKAK GQPREPQVYT LPPSREEMTK NQVSLTCLVK GFYPSDIAVE WESNGQPENN YKTTPPVLDS DGSFFLYSKL TVDKSRWQQG NVFSCSVMHE ALHNHYTQKS LSLSPGK,DIVMTQSPDS LAVSLGERAT INCKSSQSLL SGSFNYLTWY QQKPGQPPKL LIFYASTRHT GVPDRFSGSG SGTDFTLTIS SLQAEDVAVY YCHHHYNAPP TFGPGTKVDI KRTVAAPSVF IFPPSDEQLK SGTASVVCLL NNFYPREAKV QWKVDNALQS GNSQESVTEQ DSKDSTYSLS STLTLSKADY EKHKVYACEV THQGLSSPVT KSFNRGEC
- Characteristics
- Anti-ICOS / CD278 Reference Antibody (vopratelimab) is expressed from CHO. The heavy chain type is huIgG1, and the light chain type is hukappa. It has a predicted MW of 145.5 kDa.
- Purity
- >95 %
- Isotype
- IgG1
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anti-ICOS (Vopratelimab Biosimilar) antibody
Research Grade Reactivity: Human ELISA, FACS Host: Humanized Monoclonal unconjugated Recombinant Antibody
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Comment
-
Therapeutic Agents by Target and Mechanism: ICOS agonist
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Concentration
- 1 mg/mL
- Buffer
- 25 mM histidine, 8 % sucrose, 0.01 % Tween80 pH 6.2
- Storage
- 4 °C,-80 °C
- Storage Comment
- +4°C,-80°C
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- Target
- ICOS (Vopratelimab Biosimilar)
- Abstract
- ICOS (Vopratelimab Biosimilar) Products
- Target Type
- Biosimilar
- Molecular Weight
- 145.5 kDa
- UniProt
- Q9Y6W8
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