Recombinant IL1RL1 (Astegolimab Biosimilar) antibody
Quick Overview for Recombinant IL1RL1 (Astegolimab Biosimilar) antibody (ABIN7581495)
Target
Antibody Type
Reactivity
Host
Clonality
Conjugate
Application
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Expression System
- CHO Cells
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Purpose
- Anti-IL-1RL1 / ST2 / IL-33R Reference Antibody (astegolimab)
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Sequence
- EVQLVQSGAE VKKPGESLKI SCKGSGYSFT NYWIGWVRQM PGKGLEWMGI IYPGNSDTRF SPSFQGQVTI SADKSITTAY LQWSSLKASD TAMYYCARHG TSSDYYGLDV WGQGTTVTVS SASTKGPSVF PLAPCSRSTS ESTAALGCLV KDYFPEPVTV SWNSGALTSG VHTFPAVLQS SGLYSLSSVV TVPSSNFGTQ TYTCNVDHKP SNTKVDKTVE RKCCVECPPC PAPPVAGPSV FLFPPKPKDT LMISRTPEVT CVVVDVSHED PEVQFNWYVD GVEVHNAKTK PREEQFNSTF RVVSVLTVVH QDWLNGKEYK CKVSNKGLPA PIEKTISKTK GQPREPQVYT LPPSREEMTK NQVSLTCLVK GFYPSDIAVE WESNGQPENN YKTTPPMLDS DGSFFLYSKL TVDKSRWQQG NVFSCSVMHE ALHNHYTQKS LSLSPGK,DIQMTQSPSS LSASVGDRVT ITCQASQDIS NYLNWYQQKP GKAPKLLIYD ASNLETGVPS RFSGSGSGTD FTFTISSLQP EDIATYYCQQ DDNFPLTFGG GTKVEIKRTV AAPSVFIFPP SDEQLKSGTA SVVCLLNNFY PREAKVQWKV DNALQSGNSQ ESVTEQDSKD STYSLSSTLT LSKADYEKHK VYACEVTHQG LSSPVTKSFN RGEC
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Characteristics
- Anti-IL-1RL1 / ST2 / IL-33R Reference Antibody (astegolimab) is expressed from CHO. The heavy chain type is huIgG2, and the light chain type is hukappa. It has a predicted MW of 145.5 kDa.
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Purity
- >95 %
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Isotype
- IgG2SA
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Comment
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Therapeutic Agents by Target and Mechanism: IL-33R inhibitors
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Concentration
- 1 mg/mL
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Buffer
- 25 mM histidine, 8 % sucrose, 0.01 % Tween80 pH 6.2
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Storage
- 4 °C,-80 °C
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Storage Comment
- +4°C,-80°C
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- IL1RL1 (Astegolimab Biosimilar)
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Alternative Name
- IL-1RL1 (Astegolimab Biosimilar)
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Target Type
- Biosimilar
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Molecular Weight
- 145.5 kDa
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UniProt
- Q01638
Target
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