Recombinant IL6 (Siltuximab Biosimilar) antibody
Reactivity: Human
ELISA, FACS, BLI, Func, SPR
Host: Human
Monoclonal
unconjugated
Recombinant Antibody
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- Target See all IL6 (Siltuximab Biosimilar) products
- IL6 (Siltuximab Biosimilar)
- Antibody Type
- Recombinant Antibody
- Reactivity
- Human
-
Host
-
Human
- Expression System
- CHO Cells
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Clonality
- Monoclonal
-
Conjugate
- This IL6 (Siltuximab Biosimilar) antibody is un-conjugated
- Application
- ELISA, Flow Cytometry (FACS), Bio-Layer Interferometry (BLI), Functional Studies (Func), Surface Plasmon Resonance (SPR)
- Purpose
- Anti-IL-6 / IFNb2 Reference Antibody (siltuximab)
- Sequence
- EVQLVESGGK LLKPGGSLKL SCAASGFTFS SFAMSWFRQS PEKRLEWVAE ISSGGSYTYY PDTVTGRFTI SRDNAKNTLY LEMSSLRSED TAMYYCARGL WGYYALDYWG QGTSVTVSSA STKGPSVFPL APSSKSTSGG TAALGCLVKD YFPEPVTVSW NSGALTSGVH TFPAVLQSSG LYSLSSVVTV PSSSLGTQTY ICNVNHKPSN TKVDKKVEPK SCDKTHTCPP CPAPELLGGP SVFLFPPKPK DTLMISRTPE VTCVVVDVSH EDPEVKFNWY VDGVEVHNAK TKPREEQYNS TYRVVSVLTV LHQDWLNGKE YKCKVSNKAL PAPIEKTISK AKGQPREPQV YTLPPSRDEL TKNQVSLTCL VKGFYPSDIA VEWESNGQPE NNYKTTPPVL DSDGSFFLYS KLTVDKSRWQ QGNVFSCSVM HEALHNHYTQ KSLSLSPGK,QIVLIQSPAI MSASPGEKVT MTCSASSSVS YMYWYQQKPG SSPRLLIYDT SNLASGVPVR FSGSGSGTSY SLTISRMEAE DAATYYCQQW SGYPYTFGGG TKLEIKRTVA APSVFIFPPS DEQLKSGTAS VVCLLNNFYP REAKVQWKVD NALQSGNSQE SVTEQDSKDS TYSLSSTLTL SKADYEKHKV YACEVTHQGL SSPVTKSFNR GEC
- Characteristics
- Anti-IL-6 / IFNb2 Reference Antibody (siltuximab) is expressed from CHO. The heavy chain type is huIgG1, and the light chain type is hukappa. It has a predicted MW of 145.5 kDa.
- Purity
- >95 %
- Isotype
- IgG1
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anti-IL6 (Siltuximab Biosimilar) antibody
Research Grade Reactivity: Human ELISA, FACS Host: Mouse Chimeric unconjugated Recombinant Antibody
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Comment
-
Therapeutic Agents by Target and Mechanism: IL-6 inhibitors
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Concentration
- 1 mg/mL
- Buffer
- 25 mM histidine, 8 % sucrose, 0.01 % Tween80 pH 6.2
- Storage
- 4 °C,-80 °C
- Storage Comment
- +4°C,-80°C
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- Target
- IL6 (Siltuximab Biosimilar)
- Alternative Name
- IL-6 (Siltuximab Biosimilar) (IL6 (Siltuximab Biosimilar) Products)
- Target Type
- Biosimilar
- Molecular Weight
- 145.5 kDa
- UniProt
- P05231
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