Recombinant Mesothelin (Amatuximab Biosimilar) antibody

Catalog No. ABIN7581566

This anti-Mesothelin (Amatuximab Biosimilar) antibody is a Human Monoclonal antibody detecting Mesothelin (Amatuximab Biosimilar) in ELISA, FACS, BLI, Func and SPR. Suitable for Human.

Quick Overview for Recombinant Mesothelin (Amatuximab Biosimilar) antibody (ABIN7581566)

Target: Mesothelin (Amatuximab Biosimilar)

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Human

Clonality: Monoclonal

Conjugate: This Mesothelin (Amatuximab Biosimilar) antibody is un-conjugated

Application: ELISA, Flow Cytometry (FACS), Bio-Layer Interferometry (BLI), Functional Studies (Func), Surface Plasmon Resonance (SPR)

Product Details anti-Mesothelin (Amatuximab Biosimilar) Antibody

Expression System: CHO Cells

Purpose: Anti-Mesothelin Reference Antibody (amatuximab)

Sequence: QVQLQQSGPE LEKPGASVKI SCKASGYSFT GYTMNWVKQS HGKSLEWIGL ITPYNGASSY NQKFRGKATL TVDKSSSTAY MDLLSLTSED SAVYFCARGG YDGRGFDYWG SGTPVTVSSA STKGPSVFPL APSSKSTSGG TAALGCLVKD YFPEPVTVSW NSGALTSGVH TFPAVLQSSG LYSLSSVVTV PSSSLGTQTY ICNVNHKPSN TKVDKKVEPK SCDKTHTCPP CPAPELLGGP SVFLFPPKPK DTLMISRTPE VTCVVVDVSH EDPEVKFNWY VDGVEVHNAK TKPREEQYNS TYRVVSVLTV LHQDWLNGKE YKCKVSNKAL PAPIEKTISK AKGQPREPQV YTLPPSRDEL TKNQVSLTCL VKGFYPSDIA VEWESNGQPE NNYKTTPPVL DSDGSFFLYS KLTVDKSRWQ QGNVFSCSVM HEALHNHYTQ KSLSLSPGK,DIELTQSPAI MSASPGEKVT MTCSASSSVS YMHWYQQKSG TSPKRWIYDT SKLASGVPGR FSGSGSGNSY SLTISSVEAE DDATYYCQQW SKHPLTFGSG TKVEIKRTVA APSVFIFPPS DEQLKSGTAS VVCLLNNFYP REAKVQWKVD NALQSGNSQE SVTEQDSKDS TYSLSSTLTL SKADYEKHKV YACEVTHQGL SSPVTKSFNR GEC

Characteristics: Anti-Mesothelin Reference Antibody (amatuximab) is expressed from CHO. The heavy chain type is huIgG1, and the light chain type is hukappa. It has a predicted MW of 145.5 kDa.

Purity: >95 %

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

Therapeutic Agents by Target and Mechanism: MSLN inhibitors,ADCC

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: 1 mg/mL

Buffer: 25 mM histidine, 8 % sucrose, 0.01 % Tween80 pH 6.2

Storage: 4 °C,-80 °C

Storage Comment: +4°C,-80°C

Target Details for Mesothelin (Amatuximab Biosimilar)

Target: Mesothelin (Amatuximab Biosimilar)

Target Type: Biosimilar

Molecular Weight: 145.5 kDa

UniProt: Q13421