Recombinant Nectin-4 (Enfortumab Biosimilar) antibody
Quick Overview for Recombinant Nectin-4 (Enfortumab Biosimilar) antibody (ABIN7581582)
Target
Antibody Type
Reactivity
Host
Clonality
Conjugate
Application
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Expression System
- CHO Cells
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Purpose
- Anti-Nectin-4 Reference Antibody (enfortumab)
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Sequence
- EVQLVESGGG LVQPGGSLRL SCAASGFTFS SYNMNWVRQA PGKGLEWVSY ISSSSSTIYY ADSVKGRFTI SRDNAKNSLS LQMNSLRDED TAVYYCARAY YYGMDVWGQG TTVTVSSAST KGPSVFPLAP SSKSTSGGTA ALGCLVKDYF PEPVTVSWNS GALTSGVHTF PAVLQSSGLY SLSSVVTVPS SSLGTQTYIC NVNHKPSNTK VDKRVEPKSC DKTHTCPPCP APELLGGPSV FLFPPKPKDT LMISRTPEVT CVVVDVSHED PEVKFNWYVD GVEVHNAKTK PREEQYNSTY RVVSVLTVLH QDWLNGKEYK CKVSNKALPA PIEKTISKAK GQPREPQVYT LPPSREEMTK NQVSLTCLVK GFYPSDIAVE WESNGQPENN YKTTPPVLDS DGSFFLYSKL TVDKSRWQQG NVFSCSVMHE ALHNHYTQKS LSLSPGK,DIQMTQSPSS VSASVGDRVT ITCRASQGIS GWLAWYQQKP GKAPKFLIYA ASTLQSGVPS RFSGSGSGTD FTLTISSLQP EDFATYYCQQ ANSFPPTFGG GTKVEIKRTV AAPSVFIFPP SDEQLKSGTA SVVCLLNNFY PREAKVQWKV DNALQSGNSQ ESVTEQDSKD STYSLSSTLT LSKADYEKHK VYACEVTHQG LSSPVTKSFN RGEC
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Characteristics
- Anti-Nectin-4 Reference Antibody (enfortumab) is expressed from CHO. The heavy chain type is huIgG1, and the light chain type is hukappa. It has a predicted MW of 145.44 kDa.
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Purity
- >95 %
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Isotype
- IgG1
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Comment
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Therapeutic Agents by Target and Mechanism: Nectin-4 inhibitors
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Concentration
- 1 mg/mL
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Buffer
- 25 mM histidine, 8 % sucrose, 0.01 % Tween80 pH 6.2
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Storage
- 4 °C,-80 °C
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Storage Comment
- +4°C,-80°C
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- Nectin-4 (Enfortumab Biosimilar)
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Target Type
- Biosimilar
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Molecular Weight
- 145.44 kDa
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UniProt
- Q96NY8
Target
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