Recombinant PDCD1 (Nivolumab Biosimilar) antibody
Quick Overview for Recombinant PDCD1 (Nivolumab Biosimilar) antibody (ABIN7581618)
Target
Antibody Type
Reactivity
Host
Clonality
Conjugate
Application
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Expression System
 - CHO Cells
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Purpose
 - Anti-PDCD1 / PD-1 / CD279 Reference Antibody (nivolumab)
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Sequence
 - QVQLVESGGG VVQPGRSLRL DCKASGITFS NSGMHWVRQA PGKGLEWVAV IWYDGSKRYY ADSVKGRFTI SRDNSKNTLF LQMNSLRAED TAVYYCATND DYWGQGTLVT VSSASTKGPS VFPLAPCSRS TSESTAALGC LVKDYFPEPV TVSWNSGALT SGVHTFPAVL QSSGLYSLSS VVTVPSSSLG TKTYTCNVDH KPSNTKVDKR VESKYGPPCP PCPAPEFLGG PSVFLFPPKP KDTLMISRTP EVTCVVVDVS QEDPEVQFNW YVDGVEVHNA KTKPREEQFN STYRVVSVLT VLHQDWLNGK EYKCKVSNKG LPSSIEKTIS KAKGQPREPQ VYTLPPSQEE MTKNQVSLTC LVKGFYPSDI AVEWESNGQP ENNYKTTPPV LDSDGSFFLY SRLTVDKSRW QEGNVFSCSV MHEALHNHYT QKSLSLSLGK ,EIVLTQSPAT LSLSPGERAT LSCRASQSVS SYLAWYQQKP GQAPRLLIYD ASNRATGIPA RFSGSGSGTD FTLTISSLEP EDFAVYYCQQ SSNWPRTFGQ GTKVEIKRTV AAPSVFIFPP SDEQLKSGTA SVVCLLNNFY PREAKVQWKV DNALQSGNSQ ESVTEQDSKD STYSLSSTLT LSKADYEKHK VYACEVTHQG LSSPVTKSFN RGEC
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Characteristics
 - Anti-PDCD1 / PD-1 / CD279 Reference Antibody (nivolumab) is expressed from CHO. The heavy chain type is huIgG4SP, and the light chain type is hukappa. It has a predicted MW of 145.5 kDa.
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Purity
 - >95 %
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Isotype
 - IgG4 S228P
 
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Application Notes
 - Optimal working dilution should be determined by the investigator.
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Comment
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Therapeutic Agents by Target and Mechanism: PD-1 inhibitors
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Restrictions
 - For Research Use only
 
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Format
 - Lyophilized
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Concentration
 - 1 mg/mL
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Buffer
 - 25 mM histidine, 8 % sucrose, 0.01 % Tween80 pH 6.2
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Storage
 - 4 °C,-80 °C
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Storage Comment
 - +4°C,-80°C
 
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- PDCD1 (Nivolumab Biosimilar)
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Target Type
 - Biosimilar
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Molecular Weight
 - 145.5 kDa
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UniProt
 - Q15116
 
Target
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