Recombinant PDCD1 (Pembrolizumab Biosimilar) antibody

Catalog No. ABIN7581619

The Human Monoclonal anti-PDCD1 (Pembrolizumab Biosimilar) antibody has been validated for FACS, ELISA, BLI, Func and SPR. It is suitable to detect PDCD1 (Pembrolizumab Biosimilar) in samples from Human.

Quick Overview for Recombinant PDCD1 (Pembrolizumab Biosimilar) antibody (ABIN7581619)

Target: PDCD1 (Pembrolizumab Biosimilar)

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Human

Clonality: Monoclonal

Conjugate: This PDCD1 (Pembrolizumab Biosimilar) antibody is un-conjugated

Application: Flow Cytometry (FACS), ELISA, Bio-Layer Interferometry (BLI), Functional Studies (Func), Surface Plasmon Resonance (SPR)

Product Details anti-PDCD1 (Pembrolizumab Biosimilar) Antibody

Expression System: CHO Cells

Purpose: Anti-PDCD1 / PD-1 / CD279 Reference Antibody (pembrolizumab)

Sequence: QVQLVQSGVE VKKPGASVKV SCKASGYTFT NYYMYWVRQA PGQGLEWMGG INPSNGGTNF NEKFKNRVTL TTDSSTTTAY MELKSLQFDD TAVYYCARRD YRFDMGFDYW GQGTTVTVSS ASTKGPSVFP LAPCSRSTSE STAALGCLVK DYFPEPVTVS WNSGALTSGV HTFPAVLQSS GLYSLSSVVT VPSSSLGTKT YTCNVDHKPS NTKVDKRVES KYGPPCPPCP APEFLGGPSV FLFPPKPKDT LMISRTPEVT CVVVDVSQED PEVQFNWYVD GVEVHNAKTK PREEQFNSTY RVVSVLTVLH QDWLNGKEYK CKVSNKGLPS SIEKTISKAK GQPREPQVYT LPPSQEEMTK NQVSLTCLVK GFYPSDIAVE WESNGQPENN YKTTPPVLDS DGSFFLYSRL TVDKSRWQEG NVFSCSVMHE ALHNHYTQKS LSLSLGK,EIVLTQSPAT LSLSPGERAT LSCRASKGVS TSGYSYLHWY QQKPGQAPRL LIYLASYLES GVPARFSGSG SGTDFTLTIS SLEPEDFAVY YCQHSRDLPL TFGGGTKVEI KRTVAAPSVF IFPPSDEQLK SGTASVVCLL NNFYPREAKV QWKVDNALQS GNSQESVTEQ DSKDSTYSLS STLTLSKADY EKHKVYACEV THQGLSSPVT KSFNRGEC

Characteristics: Anti-PDCD1 / PD-1 / CD279 Reference Antibody (pembrolizumab) is expressed from CHO. The heavy chain type is huIgG4SP, and the light chain type is hukappa. It has a predicted MW of 145.5 kDa.

Purity: >95 %

Isotype: IgG4 S228P

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

Therapeutic Agents by Target and Mechanism: PD-1 inhibitors

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: 1 mg/mL

Buffer: 25 mM histidine, 8 % sucrose, 0.01 % Tween80 pH 6.2

Storage: 4 °C,-80 °C

Storage Comment: +4°C,-80°C

Target Details for PDCD1 (Pembrolizumab Biosimilar)

Target: PDCD1 (Pembrolizumab Biosimilar)

Target Type: Biosimilar

Molecular Weight: 145.5 kDa

UniProt: Q15116