Recombinant Trop2 (Sacituzumab Biosimilar) antibody
Quick Overview for Recombinant Trop2 (Sacituzumab Biosimilar) antibody (ABIN7581747)
Target
Antibody Type
Reactivity
Host
Clonality
Conjugate
Application
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Expression System
- CHO Cells
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Purpose
- Anti-TROP2 Reference Antibody (sacituzumab)
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Sequence
- QVQLQQSGSE LKKPGASVKV SCKASGYTFT NYGMNWVKQA PGQGLKWMGW INTYTGEPTY TDDFKGRFAF SLDTSVSTAY LQISSLKADD TAVYFCARGG FGSSYWYFDV WGQGSLVTVS SASTKGPSVF PLAPSSKSTS GGTAALGCLV KDYFPEPVTV SWNSGALTSG VHTFPAVLQS SGLYSLSSVV TVPSSSLGTQ TYICNVNHKP SNTKVDKRVE PKSCDKTHTC PPCPAPELLG GPSVFLFPPK PKDTLMISRT PEVTCVVVDV SHEDPEVKFN WYVDGVEVHN AKTKPREEQY NSTYRVVSVL TVLHQDWLNG KEYKCKVSNK ALPAPIEKTI SKAKGQPREP QVYTLPPSRE EMTKNQVSLT CLVKGFYPSD IAVEWESNGQ PENNYKTTPP VLDSDGSFFL YSKLTVDKSR WQQGNVFSCS VMHEALHNHY TQKSLSLSPG K,DIQLTQSPSS LSASVGDRVS ITCKASQDVS IAVAWYQQKP GKAPKLLIYS ASYRYTGVPD RFSGSGSGTD FTLTISSLQP EDFAVYYCQQ HYITPLTFGA GTKVEIKRTV AAPSVFIFPP SDEQLKSGTA SVVCLLNNFY PREAKVQWKV DNALQSGNSQ ESVTEQDSKD STYSLSSTLT LSKADYEKHK VYACEVTHQG LSSPVTKSFN RGEC
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Characteristics
- Anti-TROP2 Reference Antibody (sacituzumab) is expressed from CHO. The heavy chain type is huIgG1, and the light chain type is hukappa. It has a predicted MW of 145.5 kDa.
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Purity
- >95 %
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Isotype
- IgG1
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Comment
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Therapeutic Agents by Target and Mechanism: TROP2 inhibitors
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Concentration
- 1 mg/mL
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Buffer
- 25 mM histidine, 8 % sucrose, 0.01 % Tween80 pH 6.2
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Storage
- 4 °C,-80 °C
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Storage Comment
- +4°C,-80°C
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- Trop2 (Sacituzumab Biosimilar)
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Target Type
- Biosimilar
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Molecular Weight
- 145.5 kDa
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UniProt
- P09758
Target
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