GFRA1 antibody (AA 351-429) (Biotin)

Catalog No. ABIN726232

This Rabbit Polyclonal antibody specifically detects GFRA1 in WB, ELISA, IHC (p) and IHC (fro). It exhibits reactivity toward Human, Mouse and Goat.

Quick Overview for GFRA1 antibody (AA 351-429) (Biotin) (ABIN726232)

Target: GFRA1 (GDNF Family Receptor alpha 1 (GFRA1))

Reactivity: Human, Mouse, Goat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GFRA1 antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-GFRA1 Antibody (Biotin)

Binding Specificity: AA 351-429

Specificity: This antibody exhibits a secondary cross-reactivity towards Exonuclease-1 due to a 60 % contigueous sequence similarity over the immunogen range.

Cross-Reactivity: Goat, Human, Mouse

Predicted Reactivity: Rat,Dog,Cow,Pig,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GFR Alpha-1

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for GFRA1

Target: GFRA1 (GDNF Family Receptor alpha 1 (GFRA1))

Alternative Name: GDNFRA

Background:

Synonyms: GDNFR, RET1L, RETL1, TRNR1, GDNFRA, GFR-ALPHA-1, GDNF family receptor alpha-1, GDNF receptor alpha-1, GDNFR-alpha-1, RET ligand 1, TGF-beta-related neurotrophic factor receptor 1, GFRA1

Background: Receptor for GDNF. Mediates the GDNF-induced autophosphorylation and activation of the RET receptor (By similarity).

Gene ID: 2674

UniProt: P56159