DLG3 antibody (AA 1-120) (FL490)

Catalog No. ABIN7595401

This anti-DLG3 antibody is a Mouse Monoclonal antibody detecting DLG3 in IHC and ICC. Suitable for Rat.

Quick Overview for DLG3 antibody (AA 1-120) (FL490) (ABIN7595401)

Target: DLG3 (Discs, Large Homolog 3 (DLG3))

Reactivity: Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This DLG3 antibody is conjugated to FL490

Application: Immunohistochemistry (IHC), Immunocytochemistry (ICC)

Clone: N19-2

Product Details anti-DLG3 Antibody (FL490)

Binding Specificity: AA 1-120

Purpose: Anti-SAP102 Antibody FL490 Conjugate

Specificity: No off-targets reported for other MAGUK family membersPSD-95, SAP97, Chapsyn-110

Cross-Reactivity: Human, Mouse, Rabbit, Rat

Characteristics:

Description: Our Anti-SAP102 mouse monoclonal primary antibody is produced in-house from hybridoma clone N19/2. It is KO validated, detects human, mouse, and rat SAP102, and is purified by Protein A chromatography. It is great for use in IHC, ICC.

Manufacturer Comment: We produce our SAP102 mouse monoclonal primary antibody from hybridoma clone N19/2. It is great in IHC, ICC and is purified by Protein A chromatography.

Purification: Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb.

Purity: > 90 % specific antibody

Immunogen: Fusion protein amino acids 1-120 of rat SAP102 (accession number Q62936) produced recombinantly in E. Coli

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: PBS with 0.09 % azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Expiry Date: 12 months

Target Details for DLG3

Target: DLG3 (Discs, Large Homolog 3 (DLG3))

Alternative Name: SAP102

Background:

Synonyms: Disks large homolog 3 (PSD-95/SAP90-related protein 1) (Synapse-associated protein 102) (SAP-102) (SAP102)

Target Description: Synapse-Associated Protein 102, Disks large homolog 3(DLG3) or SAP102 MAGUK scaffold protein is encoded by the gene DLG3. SAP102 is a member of the MAGUK (membrane-associated guanylate kinase) protein family. SAP102 can bind to a number of adhesion molecules and receptors, including NMDA receptors and acts as a scaffold protein to mediate synaptic signaling. This protein plays a role in learning and memory and appears to be required for learning. Mutations in this gene have been associated with X-linked cognitive disability.

Gene Name Alternatives: Dlg3 Dlgh3

Molecular Weight: 105 kDa