SH3GL1 antibody (AA 287-302) (FL550)

Catalog No. ABIN7595574

The Mouse Monoclonal anti-SH3GL1 antibody has been validated for IHC and ICC. It is suitable to detect SH3GL1 in samples from Rat.

Quick Overview for SH3GL1 antibody (AA 287-302) (FL550) (ABIN7595574)

Target: SH3GL1 (SH3-Domain GRB2-Like 1 (SH3GL1))

Reactivity: Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This SH3GL1 antibody is conjugated to FL550

Application: Immunohistochemistry (IHC), Immunocytochemistry (ICC)

Clone: K51-1

Product Details anti-SH3GL1 Antibody (FL550)

Binding Specificity: AA 287-302

Purpose: Anti-SH3GL1/Endophilin A2 Antibody FL550 Conjugate

Specificity: No off-targets reported

Cross-Reactivity: Mouse, Rat

Characteristics:

Description: Our Anti-SH3GL1/Endophilin A2 mouse monoclonal primary antibody is produced in-house from hybridoma clone K51/1. It detects mouse and rat SH3GL1/Endophilin A2, and is purified by Protein A chromatography. It is great for use in IHC, ICC.

Manufacturer Comment: We produce our SH3GL1/Endophilin A2 mouse monoclonal primary antibody from hybridoma clone K51/1. It is great in IHC, ICC and is purified by Protein A chromatography.

Purification: Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb.

Purity: > 90 % specific antibody

Immunogen: Synthetic peptide amino acids 287-302 of rat SH3GL1 (accession number AAH70893)

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: PBS with 0.09 % azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Expiry Date: 12 months

Target Details for SH3GL1

Target: SH3GL1 (SH3-Domain GRB2-Like 1 (SH3GL1))

Alternative Name: Endophilin A2

Background:

Synonyms: Endophilin-A2 (Endophilin-2) (SH3 domain protein 2B) (SH3 domain-containing GRB2-like protein 1) (SH3p8)

Target Description: Endophilin-A2, SH3 domain protein 2B or SH3 Domain-Containing GRB2-Like Protein 1 is encoded by the gene Sh3gl1 and a member of the endophilin family of Src homology 3 domain-containing proteins. Endophilin-A2 is involved in endocytosis and is thought to recruit other proteins to the membrane. Endophilin-A2 may also play a role in the cell cycle. Endophilin-A2 is expressed ubiquitously in tissues. Diseases associated with SH3GL1 include Leukemia and Acute Myeloid Leukemia.

Gene Name Alternatives: Sh3gl1 Sh3p8

Molecular Weight: 43 kDa