FGF14 antibody (AA 1-252) (FL594)

Catalog No. ABIN7595672

This Mouse Monoclonal antibody specifically detects FGF14 in IHC and ICC. It exhibits reactivity toward Mouse.

Quick Overview for FGF14 antibody (AA 1-252) (FL594) (ABIN7595672)

Target: FGF14 (Fibroblast Growth Factor 14 (FGF14))

Reactivity: Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This FGF14 antibody is conjugated to FL594

Application: Immunohistochemistry (IHC), Immunocytochemistry (ICC)

Clone: N56-21

Product Details anti-FGF14 Antibody (FL594)

Binding Specificity: AA 1-252

Purpose: Anti-FGF14/FHF4 Antibody FL594 Conjugate

Specificity: Recognizes FGF14a and FGF14b No off-targets reported for FGF11, FGF12 or FGF13

Cross-Reactivity: Human, Mouse, Non-Human Primate, Rat

Characteristics:

Description: Our Anti-FGF14/FHF4 mouse monoclonal primary antibody is produced in-house from hybridoma clone N56/21. It is KO validated, detects mouse and rat FGF14/FHF4, and is purified by Protein A chromatography. It is great for use in IHC, ICC.

Manufacturer Comment: We produce our FGF14/FHF4 mouse monoclonal primary antibody from hybridoma clone N56/21. It is great in IHC, ICC and is purified by Protein A chromatography.

Purification: Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb.

Purity: > 90 % specific antibody

Immunogen: Fusion protein amino acids 1-252 (full-length) of mouse FGF14b (accession number O89096) produced recombinantly in E. Coli

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: PBS with 0.09 % azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Expiry Date: 12 months

Target Details for FGF14

Target: FGF14 (Fibroblast Growth Factor 14 (FGF14))

Alternative Name: FHF4

Background:

Synonyms: Fibroblast growth factor (FGF)

Target Description: Fibroblast growth factor 14, FHF4 or FGF14 is encoded by FGF14. FHF4 is a member of the fibroblast growth factor homologous factors family (a subfamily of fibroblast growth factors.). FHFs have a role in regulation of voltage fated sodium channels (Nav channels) and are thought to be involved in nervous system development. FGF14 in found in both the hippocampus and the cerebellum localizes to the axon initial segment. Diseases associated with FGF14 include Spinocerebellar Ataxia and Autosomal Dominant Cerebellar Ataxia.

Gene Name Alternatives: Fgf14

Molecular Weight: 28 kDa