Kv2.1/KCNB1 antibody (C-Term, Cytosolic) (FL594)

Catalog No. ABIN7595777

This Mouse Monoclonal antibody specifically detects Kv2.1/KCNB1 in IHC and ICC. It exhibits reactivity toward Rat.

Quick Overview for Kv2.1/KCNB1 antibody (C-Term, Cytosolic) (FL594) (ABIN7595777)

Target: Kv2.1/KCNB1 (KCNB1) (Potassium Voltage-Gated Channel, Shab-Related Subfamily, Member 1 (KCNB1))

Reactivity: Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This Kv2.1/KCNB1 antibody is conjugated to FL594

Application: Immunohistochemistry (IHC), Immunocytochemistry (ICC)

Grade: KO Validated

Clone: K89-34

Product Details anti-Kv2.1/KCNB1 Antibody (FL594)

Binding Specificity: AA 837-853, C-Term, Cytosolic

Purpose: Anti-Kv2.1 K+ Channel Antibody FL594 Conjugate

Sequence: HMLPGGGAHG STRDQSI

Specificity: No off-targets reported for rat Kv2.2

Cross-Reactivity: Human, Mouse

Characteristics: Our Anti-Kv2.1 K+ channel mouse monoclonal primary antibody is produced in-house from hybridoma clone K89/34. It is KO validated, detects human, mouse, and rat Kv2.1 K+ channel, and is purified by protein a chromatography. It is great for use in IHC, ICC.

Purification: Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Purity: Purified mAbs are >90 % specific antibody.

Immunogen: Synthetic peptide amino acids 837-853 (HMLPGGGAHGSTRDQSI, cytoplasmic Cterminus) of rat Kv2.1 (accession number P15387)

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: PBS with 0.09 % azide7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Expiry Date: 12 months

Target Details for Kv2.1/KCNB1

Target: Kv2.1/KCNB1 (KCNB1) (Potassium Voltage-Gated Channel, Shab-Related Subfamily, Member 1 (KCNB1))

Alternative Name: Kv2.1 K+ channel

Background:

Synonyms: Potassium voltage-gated channel subfamily B member 1 (Delayed rectifier potassium channel 1) (DRK1) (Voltage-gated potassium channel subunit Kv2.1)

Description Logic: Our Anti-Kv2.1 K+ channel mouse monoclonal primary antibody is produced from hybridoma clone K89/34. It is KO validated, detects human, mouse, and rat Kv2.1 K+ channel, and is purified by protein a chromatography. It is great for use in IHC, ICC.

Gene Name Alternatives: Kcnb1

Molecular Weight: 105-125 kDa (varies with cell background due to phosphorylation)

UniProt: P15387

Pathways: Synaptic Membrane