FGF12 antibody (AA 1-243) (FL650)

Catalog No. ABIN7595802

The Mouse Monoclonal anti-FGF12 antibody has been validated for IHC and ICC. It is suitable to detect FGF12 in samples from Human.

Quick Overview for FGF12 antibody (AA 1-243) (FL650) (ABIN7595802)

Target: FGF12 (Fibroblast Growth Factor 12 (FGF12))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This FGF12 antibody is conjugated to FL650

Application: Immunohistochemistry (IHC), Immunocytochemistry (ICC)

Clone: N94-17

Product Details anti-FGF12 Antibody (FL650)

Binding Specificity: AA 1-243

Purpose: Anti-FGF12/FHF1 Antibody FL650 Conjugate

Specificity: Recognizes FGF12b/FHF1bNo off-targets reported for FGF11/FHF3, FGF13/FHF2 or FGF14/FHF4

Cross-Reactivity: Human, Mouse, Rat

Characteristics:

Description: Our Anti-FGF12/FHF1 mouse monoclonal primary antibody is produced in-house from hybridoma clone N94/17. It detects human, mouse, and rat FGF12/FHF1, and is purified by Protein A chromatography. It is great for use in IHC, ICC.

Manufacturer Comment: We produce our FGF12/FHF1 mouse monoclonal primary antibody from hybridoma clone N94/17. It is great in IHC, ICC and is purified by Protein A chromatography.

Purification: Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb.

Purity: > 90 % specific antibody

Immunogen: Fusion protein amino acids 1-243 (full-length) of human FGF12a (accession number P61328) produced recombinantly in E. Coli

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: PBS with 0.09 % azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Expiry Date: 12 months

Target Details for FGF12

Target: FGF12 (Fibroblast Growth Factor 12 (FGF12))

Alternative Name: FHF1

Background:

Synonyms: Fibroblast growth factor 12 (FGF-12) (Fibroblast growth factor homologous factor 1) (FHF-1) (Myocyte-activating factor)

Target Description: Fibroblast growth factor 12, FHF1 or FGF12 is encoded by the gene FGF12. FHF1 is a member of the fibroblast growth factor homologous factors family (a subfamily of fibroblast growth factors.). FHFs have a role in regulation of voltage fated sodium channels (Nav channels) and are thought to be involved in nervous system development. FGF12 has been found to be expressed in the brain, eye and testis. Diseases associated with FGF12 include Early Infantile Epileptic Encephalopathy, Ebstein anomaly and Autosomal Dominant Deafness.

Gene Name Alternatives: FGF12 FGF12B FHF1

Molecular Weight: 27 kDa

Pathways: Negative Regulation of Transporter Activity