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CADM1 antibody (AA 257-388) (FL650)

This anti-CADM1 antibody is a Mouse Monoclonal antibody detecting CADM1 in ICC. Suitable for Mouse.
Catalog No. ABIN7595836

Quick Overview for CADM1 antibody (AA 257-388) (FL650) (ABIN7595836)

Target

See all CADM1 Antibodies
CADM1 (Cell Adhesion Molecule 1 (CADM1))

Reactivity

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Mouse

Host

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Mouse

Clonality

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Monoclonal

Conjugate

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This CADM1 antibody is conjugated to FL650

Application

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Immunocytochemistry (ICC)

Clone

L45-30
  • Binding Specificity

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    AA 257-388

    Purpose

    Anti-SynCAM1 Antibody FL650 Conjugate

    Specificity

    No cross-reactivity with SynCAM2 or SynCAM3

    Cross-Reactivity

    Human, Mouse, Rat

    Characteristics

    Description: Our Anti-SynCAM1 mouse monoclonal primary antibody is produced in-house from hybridoma clone L45/30. It detects human, mouse, and rat SynCAM1, and is purified by Protein A chromatography. It is great for use in ICC.

    Manufacturer Comment: We produce our SynCAM1 mouse monoclonal primary antibody from hybridoma clone L45/30. It is great in ICC and is purified by Protein A chromatography.

    Purification

    Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb.

    Purity

    > 90 % specific antibody

    Immunogen

    Fusion protein amino acids 257-388 of mouse SynCAM1 (accession number Q8R5M8), recognizes 1.4b isoform only (epitope narrowed to GLTQLPNSAEELDSEDLS) produced recombinantly in E. Coli

    Isotype

    IgG1
  • Application Notes

    Optimal working dilution should be determined by the investigator.

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    0.5 mg/mL

    Buffer

    PBS with 0.09 % azide

    Preservative

    Sodium azide

    Precaution of Use

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Storage

    4 °C,-20 °C

    Storage Comment

    Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

    Expiry Date

    12 months
  • Target

    CADM1 (Cell Adhesion Molecule 1 (CADM1))

    Alternative Name

    SynCAM1

    Background

    Synonyms: Cell adhesion molecule 1 (Immunoglobulin superfamily member 4) (IgSF4) (Nectin-like protein 2) (NECL-2) (Spermatogenic immunoglobulin superfamily) (SgIgSF) (Synaptic cell adhesion molecule) (SynCAM) (Tumor suppressor in lung cancer 1) (TSLC-1)

    Target Description: SynCAM1 cell adhesion molecule, Immunoglobulin superfamily member 4 (IgSF4), or Nectin-like protein 2 (NECL-2) is encoded by the gene CADM1 and is a member of the Immunoglobulin-like Cell Adhesion Molecules family. SynCam1 is a cell adhesion molecule involved in many cell processes including the mediation of cell-cell adhesion and assembly, neuronal migration axon growth and differentiation. SynCAM1 is expressed in many tissue types including, brain, lung, kidney, heart, spleen and liver. Diseases associated with this gene include Retroperitoneal Fibrosis and Neuromyelitis Optica Spectrum Disorder.

    Gene Name Alternatives: Cadm1 Igsf4 Necl2 Ra175 Syncam SynCam1 Tslc1

    Molecular Weight

    50 kDa

    Pathways

    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cell-Cell Junction Organization, Activated T Cell Proliferation
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