FGF13 antibody (AA 53-245) (FL650)

Catalog No. ABIN7595854

This anti-FGF13 antibody is a Mouse Monoclonal antibody detecting FGF13 in ICC. Suitable for Human.

Quick Overview for FGF13 antibody (AA 53-245) (FL650) (ABIN7595854)

Target: FGF13 (Fibroblast Growth Factor 13 (FGF13))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This FGF13 antibody is conjugated to FL650

Application: Immunocytochemistry (ICC)

Clone: N91-27

Product Details anti-FGF13 Antibody (FL650)

Binding Specificity: AA 53-245

Purpose: Anti-FGF13/FHF2 Antibody FL650 Conjugate

Specificity: Recognizes FGF13a and FGF13bNo off-targets reported for FGF11, FGF12 or FGF14 expressed in heterologous cells

Cross-Reactivity: Human, Mouse

Characteristics:

Description: Our Anti-FGF13/FHF2 mouse monoclonal primary antibody is produced in-house from hybridoma clone N91/27. It detects human and mouse FGF13/FHF2, and is purified by Protein A chromatography. It is great for use in ICC.

Manufacturer Comment: We produce our FGF13/FHF2 mouse monoclonal primary antibody from hybridoma clone N91/27. It is great in ICC and is purified by Protein A chromatography.

Purification: Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb.

Purity: > 90 % specific antibody

Immunogen: Fusion protein amino acids 53-245 of human FGF13a (accession number Q92913) produced recombinantly in E. Coli

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: PBS with 0.09 % azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Expiry Date: 12 months

Target Details for FGF13

Target: FGF13 (Fibroblast Growth Factor 13 (FGF13))

Alternative Name: FHF2

Background:

Synonyms: Fibroblast growth factor 13 (FGF-13) (Fibroblast growth factor homologous factor 2) (FHF-2)

Target Description: Fibroblast growth factor 13, FHF2 or FGF13 is encoded by the gene FGF13. FHF2 is a member of the fibroblast growth factor homologous factors family (a subfamily of fibroblast growth factors.). FHFs have a role in regulation of voltage fated sodium channels (Nav channels) and are thought to be involved in nervous system development. FGF13 is expressed in the nervous system and other tissues. Diseases associated with FGF13 include X-Linked Congenital Generalized Hypertrichosis and Wildervanck Syndrome.

Gene Name Alternatives: FGF13 FHF2

Molecular Weight: 28 kDa

Pathways: Regulation of Cell Size