FGF11 antibody (AA 55-216) (FL650)

Catalog No. ABIN7595856

The Mouse Monoclonal anti-FGF11 antibody has been validated for ICC. It is suitable to detect FGF11 in samples from Human.

Quick Overview for FGF11 antibody (AA 55-216) (FL650) (ABIN7595856)

Target: FGF11 (Fibroblast Growth Factor 11 (FGF11))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This FGF11 antibody is conjugated to FL650

Application: Immunocytochemistry (ICC)

Clone: N92-14

Product Details anti-FGF11 Antibody (FL650)

Binding Specificity: AA 55-216

Purpose: Anti-FGF11/FHF3 Antibody FL650 Conjugate

Specificity: No off-targets reported for FGF12, FGF13 or FGF14 in heterologous cells

Cross-Reactivity: Human, Mouse

Characteristics:

Description: Our Anti-FGF11/FHF3 mouse monoclonal primary antibody is produced in-house from hybridoma clone N92/14. It detects human and mouse FGF11/FHF3, and is purified by Protein A chromatography. It is great for use in ICC.

Manufacturer Comment: We produce our FGF11/FHF3 mouse monoclonal primary antibody from hybridoma clone N92/14. It is great in ICC and is purified by Protein A chromatography.

Purification: Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb.

Purity: > 90 % specific antibody

Immunogen: Fusion protein amino acids 55-216 of human FGF11a (accession number Q92914) produced recombinantly in E. Coli

Isotype: IgG2b

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: PBS with 0.09 % azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Expiry Date: 12 months

Target Details for FGF11

Target: FGF11 (Fibroblast Growth Factor 11 (FGF11))

Alternative Name: FHF3

Background:

Synonyms: Fibroblast growth factor 11 (FGF-11) (Fibroblast growth factor homologous factor 3) (FHF-3)

Target Description: Fibroblast growth factor 11, FHF3 or FGF11 is encoded by the gene FGF11. FHF3 is a member of the fibroblast growth factor homologous factors family (a subfamily of fibroblast growth factors.). FHFs have a role in regulation of voltage fated sodium channels (Nav channels) and are thought to be involved in nervous system development. FHF3 is expressed in the Nervous system. Diseases associated with FGF11 include Congenital Myasthenic Syndrome 2A and Congenital Myasthenic Syndrome.

Gene Name Alternatives: FGF11 FHF3

Molecular Weight: 25 kDa