IRF5 antibody (AA 176-240)

Catalog No. ABIN7596023

This anti-IRF5 antibody is a Mouse Monoclonal antibody detecting IRF5 in WB, ELISA, IF, ICC and FACS. Suitable for Human.

Quick Overview for IRF5 antibody (AA 176-240) (ABIN7596023)

Target: IRF5 (Interferon Regulatory Factor 5 (IRF5))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This IRF5 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC), Flow Cytometry (FACS)

Clone: 10T1

Product Details anti-IRF5 Antibody

Binding Specificity: AA 176-240

Purpose: Human IRF5 antibody

Purification: protein-A affinity chromatography

Immunogen: Recombinant human IRF-5 (176-240aa) purified from E. coli

Isotype: IgG1 kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% glycero

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.

Target Details for IRF5

Target: IRF5 (Interferon Regulatory Factor 5 (IRF5))

Alternative Name: IRF5

Background: Interferon regulatory factor 5 (IRF-5) is a member of IRF family, which plays a critical role in the regulation of genes induced by viral infection, immunostimulation and cell growth regulation. The expression of IRF-5 is limited to lymphoid organs, dendritic cells, and peripheral blood lymphocytes, but is not expressed in numerous leukemia and lymphoma cell lines. Three IRFs (IRF-3, IRF-5, IRF-7) function as direct transducers of virus-mediated signaling and play a critical role in the expression of type I interferon genes and some chemokines.

NCBI Accession: NP_116032

Pathways: TLR Signaling, Autophagy