CRYAA antibody (AA 1-173)

Catalog No. ABIN7596055

The Mouse Monoclonal anti-CRYAA antibody has been validated for WB and ELISA. It is suitable to detect CRYAA in samples from Human.

Quick Overview for CRYAA antibody (AA 1-173) (ABIN7596055)

Target: CRYAA (Crystallin, alpha A (CRYAA))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CRYAA antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Clone: C9F2

Product Details anti-CRYAA Antibody

Binding Specificity: AA 1-173

Purpose: Human Crystallin alpha A/CRYAA antibody

Purification: protein-A affinity chromatography

Immunogen: Recombinant human AlphaA Crystallin/CRYAA (1-173aa) purified from E. coli

Isotype: IgG1 kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% glycero

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.

Target Details for CRYAA

Target: CRYAA (Crystallin, alpha A (CRYAA))

Alternative Name: Crystallin alpha A/CRYAA

Background: Alpha-crystallins, a major protein of the ocular lens, are thought to play a role in maintaining lens transparency,which are composed of two gene products alpha-A and alpha-B, for acidic and basic, respectively.alpha-crystallins can be induced by heat shock and are members of the small heat shock protein (sHSP). They actas molecular chaperones and hold unfolded or misfolded proteins in large, water-soluble low molecular weightaggregates. These heterogeneous aggregates consist of 30-40 subunits of the alpha-A and alpha-B subunitshave a 3:1 ratio, respectively. Two additional function of alpha-crystallins are an autokinase activity and theparticipation in the intracellular architecture.

NCBI Accession: NP_000385

Pathways: M Phase